1. Wā Prothrombin (PT)

Ko te nuinga e whakaatu ana i te ahuatanga o te punaha coagulation o waho, e whakamahia ana te INR ki te aro turuki i nga anticoagulants waha.Ko te PT he tohu nui mo te tohu o te ahua prethrombotic, DIC me te mate ate.Ka whakamahia hei whakamatautau tirotiro mo te punaha coagulation exogenous, he tikanga nui ano hoki mo te whakahaere horopeta haumanu a-waha a-waha.

Ko te PTA<40% e tohu ana i te necrosis nui o nga pūtau ate me te heke iho o te whakahiatotanga o nga take coagulation.Hei tauira, 30%

Ka kitea te roanga i:

a.Ko te nui me te kino o te kino o te ate he mea nui na te whakatipuranga o te prothrombin me nga mea e pa ana ki te whakaheke toto.

b.He iti te VitK, ka hiahiatia a VitK ki te whakahiato i nga mea II, VII, IX, me X. Ki te kore e ranea te VitK, ka heke te whakaputa me te roa o te wa prothrombin.Ka kitea ano i roto i te mate obstructive jaundice.

C. DIC (diffuse intravascular coagulation), e pau ana i te nui o nga take coagulation na te nui o te thrombosis microvascular.

d.Te whakaheke toto mahorahora o te whanau hou, te korenga o te prothrombin i whanau mai i te rongoa anticoagulant.

Whakapoto ka kitea i:

I te wa kei roto te toto i te ahua hypercoagulable (pērā i te DIC wawe, te mate o te myocardial), nga mate thrombotic (pēnei i te thrombosis cerebral), etc.

 

2. Te wa thrombin (TT)

Ko te nuinga e whakaatu ana i te wa ka huri te fibrinogen ki te fibrin.

Ka kitea te roanga i roto i: te nui o te heparin, te matū heparinoid ranei, te pikinga o te mahi AT-III, te nui rereke me te kounga o te fibrinogen.DIC taiwhanga hyperfibrinolysis, iti (kao) fibrinoenemia, hemoglobinemia rereke, toto fibrin (proto) hua whakaheke (FDPs) piki ake.

Ko te whakahekenga kaore he hiranga haumanu.

 

3. Whakahohehia te wa thromboplastin wahanga (APTT)

Ko te nuinga o te waa e whakaatu ana i te ahuatanga o te punaha coagulation endogenous, ka whakamahia tonu ki te aro turuki i te inenga o te heparin.Ko te whakaata i nga taumata o nga mea whakaheke VIII, IX, XI, XII i roto i te plasma, he whakamatautau tirotiro mo te punaha coagulation endogenous.Ka whakamahia te APTT ki te aro turuki i te rongoa heparin anticoagulation.

Ka kitea te roanga i:

a.Te korenga o nga mea whakaheke toto VIII, IX, XI, XII:

b.Tauwehe Coagulation II, V, X me te whakaiti fibrinogen tokoiti;

C. He matū anticoagulant penei i te heparin;

d, kua piki ake nga hua whakaheke fibrinogen;e, DIC.

Whakapoto ka kitea i:

Te ahua o te hypercoagulable: Mena ka uru te matū procoagulant ki roto i te toto ka piki ake te mahi o nga mea whakaheke, me etahi atu:

 

4.Fibrinogen plasma (FIB)

Ko te nuinga e whakaatu ana i te ihirangi o te fibrinogen.Ko te Plasma fibrinogen te pūmua whakakoi me te nui o te ihirangi o nga mea whakakoi katoa, a he tauwehenga whakautu whakapeka.

Ka nui ake te kitea i roto i: weranga, mate huka, mate whakapeka, mate kohi, mate pukupuku, endocarditis kitakita subacute, haputanga, pneumonia, cholecystitis, pericarditis, sepsis, nephrotic syndrome, uremia, infarction myocardial acute.

Ko te whakahekenga ka kitea i roto i: He rerekee o te whanautanga fibrinogen, DIC momi i te wahanga hypocoagulation, te fibrinolysis tuatahi, te mate kakā nui, te ate cirrhosis.

 

5.D-Dimer (D-Dimer)

Ko te nuinga e whakaatu ana i te mahi o te fibrinolysis me te tohu hei whakatau i te aroaro o te kore ranei o te thrombosis me te fibrinolysis tuarua i roto i te tinana.

Ko te D-dimer he hua whakaheke motuhake o te fibrin hono-whakawhitinga, ka piki ake te plasma i muri noa iho i te thrombosis, na reira he tohu irapoi nui mo te tohu o te thrombosis.

I tino piki ake te D-dimer i roto i te hyperactivity fibrinolysis tuarua, engari kaore i piki ake i te hyperactivity fibrinolysis tuatahi, he tohu nui mo te wehewehe i nga mea e rua.

Ka kitea te pikinga i roto i nga mate penei i te thrombosis vein hohonu, te pulmonary embolism, me te DIC hyperfibrinolysis tuarua.