1. Oge prothrombin (PT)

Ọ na-egosipụtakarị ọnọdụ nke sistemu coagulation nke exogenous, nke a na-ejikarị INR na-enyocha ọgwụ mgbochi ọnụ.PT bụ ihe ngosi dị mkpa maka nchọpụta nke ọnọdụ prethrombotic, DIC na ọrịa imeju.A na-eji ya dị ka ule nyocha maka sistemu coagulation exogenous ma bụrụkwa ụzọ dị mkpa e si ejikwa usoro ọgwụgwọ ọgwụ mgbochi ọnụ.

PTA <40% na-egosi nnukwu necrosis nke mkpụrụ ndụ imeju na mbelata njikọ nke ihe coagulation.Dịka ọmụmaatụ, 30%

A na-ahụ ogologo oge na:

a.Mbibi imeju buru ibu ma dị njọ bụ n'ihi mmepụta nke prothrombin na ihe ndị metụtara clotting.

b.VitK na-ezughị ezu, VitK chọrọ iji synthesize ihe II, VII, IX, na X. Mgbe VitK ezughị ezu, mmepụta ahụ na-ebelata na oge prothrombin na-adịte aka.A na-ahụkwa ya na jaundice obstructive.

C. DIC (na-ekesa coagulation intravascular), nke na-eri ọtụtụ ihe na-akpata coagulation n'ihi nnukwu thrombosis microvascular.

d.Ọbara ọgbụgba na-apụtaghị ìhè nwa amụrụ ọhụrụ, enweghị ọgwụgwọ mgbochi ọrịa prothrombin.

Shorten hụrụ na:

Mgbe ọbara dị na ọnọdụ hypercoagulable (dị ka mmalite DIC, infarction myocardial), ọrịa thrombotic (dịka ụbụrụ ụbụrụ ụbụrụ), wdg.

 

2. Oge thrombin (TT)

Na-egosipụtakarị oge mgbe fibrinogen na-aghọ fibrin.

A na-ahụ ogologo oge na: ịba ụba heparin ma ọ bụ heparinoids, ịba ụba ọrụ AT-III, ọnụọgụ na-adịghị mma na àgwà fibrinogen.DIC hyperfibrinolysis ogbo, obere (enweghị) fibrinogenemia, hemoglobinemia na-adịghị mma, ọbara fibrin (proto) ngwaahịa mbibi (FDPs) mụbara.

Mbelata ahụ enweghị mkpa ụlọ ọgwụ.

 

3. Oge thromboplastin na-arụ ọrụ (APTT)

Ọ na-egosipụtakarị ọnọdụ nke sistemu coagulation endogenous ma a na-ejikarị ya nyochaa usoro ọgwụgwọ heparin.N'igosi ọkwa nke coagulation factor VIII, IX, XI, XII na plasma, ọ bụ ule nyocha maka sistemu coagulation endogenous.A na-ejikarị APTT iji nyochaa ọgwụgwọ mgbochi ọrịa heparin.

A na-ahụ ogologo oge na:

a.Enweghị ihe kpatara coagulation VIII, IX, XI, XII:

b.Ihe kpatara coagulation II, V, X na mbelata fibrinogen ole na ole;

C. E nwere ihe ndị na-eme ka ọbara ọgbụgba dị ka heparin;

d, ngwaahịa mmebi fibrinogen mụbara;e, DIC.

Shorten hụrụ na:

Ọnọdụ hypercoagulable: Ọ bụrụ na ihe procoagulant na-abanye n'ọbara na ọrụ nke coagulation na-abawanye, wdg.:

 

4.Plasma fibrinogen (FIB)

Na-egosipụtakarị ọdịnaya fibrinogen.Plasma fibrinogen bụ protein coagulation nke nwere ọdịnaya kachasị elu nke ihe niile na-akpata coagulation, na ọ bụ nnukwu ihe nzaghachi nke oge.

Mmụba a na-ahụ na: ọkụ, ọrịa shuga, nnukwu ọrịa, nnukwu ụkwara nta, cancer, subacute bacteria endocarditis, afọ ime, oyi baa, cholecystitis, pericarditis, sepsis, nephrotic syndrome, uremia, nnukwu myocardial infarction.

Mbelata hụrụ na: Congenital fibrinogen abnormality, DIC imefusị hypocoagulation oge, isi fibrinolysis, oké ịba ọcha n'anya, imeju cirrhosis.

 

5.D-Dimer (D-Dimer)

Ọ na-egosipụtakarị ọrụ fibrinolysis ma bụrụ ihe ngosi iji chọpụta ọnụnọ ma ọ bụ enweghị thrombosis na fibrinolysis nke abụọ na ahụ.

D-dimer bụ ngwaahịa na-emebi emebi nke fibrin jikọtara ọnụ, nke na-abawanye na plasma naanị mgbe thrombosis gasịrị, yabụ, ọ bụ akara dị mkpa nke molekul maka nchoputa nke thrombosis.

D-dimer mụbara nke ukwuu na hyperactivity fibrinolysis nke abụọ, mana ọ naghị abawanye na hyperactivity fibrinolysis bụ isi, nke bụ ihe ngosi dị mkpa maka ịmata ọdịiche abụọ ahụ.

A na-ahụ mmụba ahụ na ọrịa ndị dị ka thrombosis miri emi, pulmonary embolism, na hyperfibrinolysis nke abụọ DIC.