1. Oge Prothrombin (PT)

Ọ na-egosipụtakarị ọnọdụ nke sistemu coagulation exogenous, nke a na-ejikarị INR enyocha ọgwụ mgbochi afọ ime. PT bụ ihe ngosi dị mkpa maka nchọpụta ọnọdụ tupu thrombosis, DIC na ọrịa imeju. A na-eji ya dị ka ule nyocha maka sistemu coagulation exogenous ma bụrụkwa ụzọ dị mkpa isi chịkwaa dose nke ọgwụgwọ mgbochi coagulation n'ọnụ.

PTA <40% na-egosi nnukwu necrosis nke mkpụrụ ndụ imeju na mbelata njikọ nke ihe ndị na-akpata coagulation. Dịka ọmụmaatụ, 30%

A na-ahụ ịgbatị oge ahụ na:

a. Mmebi imeju dị oke njọ na nke dị njọ bụ n'ihi mmepụta nke prothrombin na ihe ndị metụtara ya.

b. A chọrọ VitK zuru oke iji mepụta ihe II, VII, IX, na X. Ọ bụrụ na VitK ezughi oke, mmepụta ya na-ebelata ma oge prothrombin na-agbatị. A na-ahụkwa ya na jaundice na-egbochi.

C. DIC (ịkọwa ọbara n'ime akwara), nke na-eri ọtụtụ ihe ndị na-akpata coagulation n'ihi nnukwu thrombosis nke microvascular.

d. Ọbara ọgbụgba nwa amụrụ ọhụrụ, enweghị ọgwụgwọ anticoagulant nke prothrombin mgbe a mụrụ ya.

E hụrụ ya na:

Mgbe ọbara dị n'ọnọdụ hypercoagulable (dịka DIC mbụ, myocardial infarction), ọrịa thrombotic (dịka cerebral thrombosis), wdg.

 

2. Oge Thrombin (TT)

Nke a na-egosipụtakarị oge fibrinogen na-aghọ fibrin.

A na-ahụ ogologo oge a na: mmụba nke ihe heparin ma ọ bụ heparinoid, mmụba nke ọrụ AT-III, ọnụọgụ na-adịghị mma na ịdị mma nke fibrinogen. Ọkwa DIC hyperfibrinolysis, obere fibrinogenemia (enweghị), hemoglobinemia na-adịghị mma, ngwaahịa mbibi fibrin (proto) n'ọbara (FDPs) mụbara.

Mbelata ahụ enweghị ihe ọ bụla dị mkpa maka ọgwụgwọ.

 

3. Oge thromboplastin nke akụkụ ya (APTT) na-arụ ọrụ

Ọ na-egosipụtakarị ọnọdụ nke sistemu coagulation endogenous ma a na-ejikarị ya enyocha etu heparin si arụ ọrụ. N'igosipụta ọkwa nke ihe coagulation VIII, IX, XI, XII na plasma, ọ bụ ule nyocha maka sistemu coagulation endogenous. A na-ejikarị APTT enyocha ọgwụgwọ heparin anticoagulation.

A na-ahụ ịgbatị oge ahụ na:

a. Enweghị ihe ndị na-eme ka ọbara dị n'ọbara nke VIII, IX, XI, XII:

b. Mbelata njikọ nke II, V, X na fibrinogen ole na ole;

C. E nwere ihe ndị na-egbochi ọbara ọgbụgba dịka heparin;

d, ngwaahịa mmebi fibrinogen mụbara; e, DIC.

E hụrụ ya na:

Ọnọdụ nke na-agbakọta n'ọbara: Ọ bụrụ na ihe na-agbakọta n'ọbara abanye n'ọbara ma ọrụ nke ihe ndị na-agbakọta n'ọbara na-abawanye, wdg.:

 

4.Fibrinogen nke plasma (FIB)

Ọ na-egosipụtakarị ọdịnaya nke fibrinogen. Plasma fibrinogen bụ protein coagulation nke nwere ọdịnaya kachasị elu nke ihe niile na-akpata coagulation, ọ bụkwa ihe na-akpata mmeghachi omume ngwa ngwa.

A na-ahụ mmụba na: ọkụ, ọrịa shuga, ọrịa akụrụ, ụkwara nta, kansa, endocarditis nje bacteria subacute, afọ ime, oyi baa, cholecystitis, pericarditis, sepsis, nephrotic syndrome, uremia, nnukwu myocardial infarction.

Mbelata a hụrụ na: Nsogbu fibrinogen sitere n'ọmụmụ, oge DIC na-ebelata hypocoagulation, fibrinolysis nke mbụ, oke ịba ọcha n'anya, imeju cirrhosis.

 

5.D-Dimer (D-Dimer)

Ọ na-egosipụtakarị ọrụ nke fibrinolysis ma bụrụkwa ihe ngosi iji chọpụta ọnụnọ ma ọ bụ enweghị thrombosis na fibrinolysis nke abụọ n'ahụ.

D-dimer bụ ngwaahịa mmebi kpọmkwem nke fibrin cross-linked, nke na-abawanye na plasma naanị mgbe thrombosis gasịrị, yabụ ọ bụ ihe dị mkpa maka nchọpụta nke thrombosis.

D-dimer mụbara nke ukwuu na oke ọrụ fibrinolysis nke abụọ, mana ọ baghị ụba na oke ọrụ fibrinolysis nke mbụ, nke bụ ihe ngosi dị mkpa maka ịmata ọdịiche dị n'etiti ha abụọ.

A na-ahụ mmụba a n'ọrịa dịka thrombosis nke akwara miri emi, embolism nke akpa ume, na DIC secondary hyperfibrinolysis.