1. Lub Sijhawm Prothrombin (PT)

Nws feem ntau yog qhia txog qhov xwm txheej ntawm lub cev coagulation sab nraud, uas INR feem ntau siv los saib xyuas cov tshuaj anticoagulants hauv qhov ncauj. PT yog ib qho cim tseem ceeb rau kev kuaj mob prethrombotic, DIC thiab kab mob siab. Nws yog siv los ua kev kuaj mob rau lub cev coagulation sab nraud thiab tseem yog ib txoj hauv kev tseem ceeb ntawm kev tswj hwm koob tshuaj hauv qhov ncauj.

PTA <40% qhia txog necrosis loj ntawm cov hlwb siab thiab txo qis kev tsim cov coagulation factors. Piv txwv li, 30%

Qhov ntev yog pom hauv:

a. Kev puas tsuaj loj heev thiab mob siab heev feem ntau yog vim muaj cov prothrombin thiab lwm yam teeb meem ntsig txog kev ntshav txhaws.

b. Tsis txaus VitK, VitK yog qhov yuav tsum tau los tsim cov yam II, VII, IX, thiab X. Thaum VitK tsis txaus, kev tsim khoom yuav txo qis thiab lub sijhawm prothrombin yuav ntev dua. Nws kuj pom muaj nyob rau hauv kev mob daj ntseg.

C. DIC (diffuse intravascular coagulation), uas siv ntau yam coagulation factors vim muaj microvascular thrombosis ntau heev.

d. Cov menyuam mos uas los ntshav yam tsis tau npaj tseg, cov prothrombin uas yug los tsis muaj kev kho mob anticoagulant.

Ua kom luv dua pom hauv:

Thaum cov ntshav nyob rau hauv lub xeev hypercoagulable (xws li DIC thaum ntxov, myocardial infarction), cov kab mob thrombotic (xws li cerebral thrombosis), thiab lwm yam.

 

2. Lub sijhawm Thrombin (TT)

Feem ntau yog qhia txog lub sijhawm uas fibrinogen hloov mus ua fibrin.

Qhov ntev ntev pom tau hauv: cov tshuaj heparin lossis heparinoid ntau ntxiv, kev ua haujlwm AT-III ntau ntxiv, qhov ntau thiab zoo ntawm fibrinogen tsis zoo. DIC hyperfibrinolysis theem, qis (tsis muaj) fibrinogenemia, hemoglobinemia tsis zoo, cov ntshav fibrin (proto) degradation products (FDPs) nce ntxiv.

Qhov kev txo qis tsis muaj qhov tseem ceeb hauv kev kho mob.

 

3. Lub sijhawm ua haujlwm ib nrab thromboplastin (APTT)

Nws feem ntau yog qhia txog qhov xwm txheej ntawm lub cev coagulation endogenous thiab feem ntau yog siv los saib xyuas qhov koob tshuaj ntawm heparin. Kev qhia txog cov theem ntawm cov coagulation factors VIII, IX, XI, XII hauv plasma, nws yog kev kuaj xyuas rau lub cev coagulation endogenous. APTT feem ntau yog siv los saib xyuas heparin anticoagulation therapy.

Qhov ntev yog pom hauv:

a. Tsis muaj cov yam ntxwv ntshav khov VIII, IX, XI, XII:

b. Cov yam ntxwv coagulation II, V, X thiab fibrinogen txo qis ob peb tug;

C. Muaj cov tshuaj anticoagulant xws li heparin;

d, cov khoom puas tsuaj ntawm fibrinogen nce ntxiv; e, DIC.

Ua kom luv dua pom hauv:

Lub xeev hypercoagulable: Yog tias cov tshuaj procoagulant nkag mus rau hauv cov ntshav thiab cov haujlwm ntawm cov yam ntxwv coagulation nce ntxiv, thiab lwm yam.:

 

4.Cov ntshav fibrinogen (FIB)

Feem ntau qhia txog cov ntsiab lus ntawm fibrinogen. Plasma fibrinogen yog cov protein coagulation uas muaj cov ntsiab lus siab tshaj plaws ntawm txhua yam coagulation factors, thiab nws yog ib qho kev teb sai sai.

Nce ntxiv pom muaj nyob rau hauv: kub hnyiab, ntshav qab zib, kev kis kab mob sai sai, mob ntsws ntsws sai sai, mob qog noj ntshav, mob endocarditis subacute bacterial, cev xeeb tub, mob ntsws, cholecystitis, pericarditis, sepsis, nephrotic syndrome, uremia, mob myocardial infarction sai sai.

Kev txo qis pom muaj nyob rau hauv: Congenital fibrinogen abnormality, DIC wasting hypocoagulation phase, primary fibrinolysis, hepatitis hnyav, hepatitis cirrhosis.

 

5.D-Dimer (D-Dimer)

Nws feem ntau qhia txog kev ua haujlwm ntawm fibrinolysis thiab yog qhov qhia tau los txiav txim siab qhov muaj lossis tsis muaj thrombosis thiab fibrinolysis theem ob hauv lub cev.

D-dimer yog ib qho khoom tawg tshwj xeeb ntawm cov fibrin txuas, uas nce hauv plasma tsuas yog tom qab thrombosis, yog li nws yog ib qho cim tseem ceeb rau kev kuaj mob thrombosis.

D-dimer nce ntxiv ntau hauv kev ua haujlwm fibrinolysis theem ob, tab sis tsis nce ntxiv hauv kev ua haujlwm fibrinolysis thawj, uas yog qhov qhia tseem ceeb rau kev paub qhov txawv ntawm ob qho no.

Qhov kev nce ntxiv no pom muaj nyob rau hauv cov kab mob xws li cov hlab ntsha tob thrombosis, pulmonary embolism, thiab DIC secondary hyperfibrinolysis.