I-pneumonia entsha ye-coronavirus (COVID-19) ka-2019 isakazeke emhlabeni jikelele. Izifundo zangaphambilini zikhombisile ukuthi ukutheleleka kwe-coronavirus kungaholela ezinkingeni zokuqina kwemithambo yegazi, okubonakala kakhulu njengesikhathi eside esisebenzayo se-partial thromboplastin (APTT), i-thrombocytopenia, i-D-dimer (DD) Amazinga aphezulu kanye ne-disseminated intravascular coagulation (DIC), ezihlotshaniswa nokufa okuphezulu.

Ukuhlaziywa kwakamuva kwe-meta-analysis yomsebenzi wokujiya kwegazi ezigulini ezine-COVID-19 (kufaka phakathi izifundo eziyi-9 eziphindaphindayo ezineziguli eziyi-1 105) kubonise ukuthi uma kuqhathaniswa neziguli ezincane, iziguli ezine-COVID-19 ezinzima zazinamanani aphezulu kakhulu e-DD, isikhathi se-Prothrombin (PT) sasiside; i-DD ekhuphukile yayiyisici esiyingozi sokubhebhetheka kanye nesici esiyingozi sokufa. Kodwa-ke, ukuhlaziywa kwe-Meta okukhulunywe ngakho ngenhla kufake izifundo ezimbalwa futhi kufake nezifundo ezimbalwa zocwaningo. Muva nje, izifundo eziningi zezokwelapha ezinkulu mayelana nomsebenzi wokujiya kwegazi ezigulini ezine-COVID-19 zishicilelwe, futhi izici zokujiya kwegazi ezigulini ezine-COVID-19 ezibikwe ezifundweni ezahlukahlukene nazo azinjalo.

Ucwaningo lwamuva nje olusekelwe kudatha kazwelonke lukhombisile ukuthi ama-40% eziguli ze-COVID-19 asengozini enkulu ye-venous thromboembolism (VTE), kanti ama-11% eziguli ezisengozini enkulu athuthuka ngaphandle kwezinyathelo zokuvimbela. I-VTE. Imiphumela yolunye ucwaningo ikhombisile nokuthi ama-25% eziguli ze-COVID-19 ezibucayi athole i-VTE, kanti izinga lokufa kweziguli ezine-VTE laliphezulu ngama-40%. Lukhombisa ukuthi iziguli ezine-COVID-19, ikakhulukazi iziguli ezibucayi noma ezigula kakhulu, zinengozi ephezulu ye-VTE. Isizathu esingenzeka ukuthi iziguli ezibucayi nezigula kakhulu zinezifo eziningi eziyisisekelo, njengomlando we-cerebral infarction kanye nesimila esibi, okuyizinto eziyingozi ze-VTE, kanti iziguli ezibucayi nezigula kakhulu zilala embhedeni isikhathi eside, zilaliswe imizwa, zingasebenzi, futhi zibekwe kumadivayisi ahlukahlukene. Izindlela zokwelapha ezifana namapayipi nazo ziyizici eziyingozi ze-thrombosis. Ngakho-ke, ezigulini ze-COVID-19 ezibucayi nezigula kakhulu, ukuvimbela i-VTE ngomshini, njengezitokisi ezinwebekayo, ipompo evuvukalayo ngezikhathi ezithile, njll., kungenziwa; ngesikhathi esifanayo, umlando wezokwelapha wesiguli odlule kufanele uqondwe ngokugcwele, futhi umsebenzi wokugaya igazi wesiguli kufanele uhlolwe ngesikhathi esifanele. Ezigulini, ukuvimbela ukugaya igazi kungaqalwa uma kungekho ziphazamiso.

Imiphumela yamanje iphakamisa ukuthi izinkinga zokuqina kwamalungu omzimba zivame kakhulu ezigulini ze-COVID-19 ezibucayi, ezigula kakhulu, nezifayo. Inani lama-platelet, i-DD kanye ne-PT ​​lihlobene nobunzima besifo futhi lingasetshenziswa njengezinkomba zokuxwayisa zakuqala zokuwohloka kwesifo ngesikhathi sokulaliswa esibhedlela.