Chibayo chatsopano cha coronavirus (COVID-19) cha 2019 chafalikira padziko lonse lapansi. Kafukufuku wakale wasonyeza kuti matenda a coronavirus angayambitse matenda otsekeka kwa magazi, makamaka omwe amawonetsedwa ngati nthawi yayitali yogwira ntchito ya thromboplastin (APTT), thrombocytopenia, D-dimer (DD) Kuchuluka kwa magazi m'thupi komanso kufalikira kwa magazi m'mitsempha (DIC), zomwe zimagwirizanitsidwa ndi imfa zambiri.

Kusanthula kwaposachedwa kwa meta-analysis ya ntchito yotsekeka kwa magazi mwa odwala omwe ali ndi COVID-19 (kuphatikiza maphunziro 9 obwerezabwereza omwe ali ndi odwala 1 105) kwawonetsa kuti poyerekeza ndi odwala ofatsa, odwala oopsa a COVID-19 anali ndi DD yapamwamba kwambiri, nthawi ya Prothrombin (PT) inali yayitali; kuwonjezeka kwa DD kunali chiopsezo cha kukulirakulira komanso chiopsezo cha imfa. Komabe, kusanthula kwa Meta komwe kwatchulidwa pamwambapa kunaphatikizapo maphunziro ochepa ndipo kunaphatikizapo maphunziro ochepa ofufuza. Posachedwapa, maphunziro akuluakulu azachipatala okhudza ntchito yotsekeka kwa magazi mwa odwala omwe ali ndi COVID-19 afalitsidwa, ndipo mawonekedwe a kutsekeka kwa magazi kwa odwala omwe ali ndi COVID-19 omwe adanenedwa m'maphunziro osiyanasiyana nawonso si enieni.

Kafukufuku waposachedwa wochokera ku deta ya dziko lonse wasonyeza kuti 40% ya odwala a COVID-19 ali pachiwopsezo chachikulu cha venous thromboembolism (VTE), ndipo 11% ya odwala omwe ali pachiwopsezo chachikulu amatenga matendawa popanda njira zodzitetezera. VTE. Zotsatira za kafukufuku wina zawonetsanso kuti 25% ya odwala omwe ali pachiwopsezo chachikulu cha COVID-19 adayamba kudwala VTE, ndipo chiwerengero cha imfa cha odwala omwe ali ndi VTE chinali chokwera kufika pa 40%. Zikuwonetsa kuti odwala omwe ali ndi COVID-19, makamaka odwala omwe ali pachiwopsezo chachikulu kapena omwe ali pachiwopsezo chachikulu, ali pachiwopsezo chachikulu cha VTE. Chifukwa chake n'chakuti odwala omwe ali pachiwopsezo chachikulu komanso omwe ali pachiwopsezo chachikulu ali ndi matenda enaake, monga mbiri ya infarction ya ubongo ndi chotupa choipa, zomwe zonse ndi zinthu zomwe zimayambitsa VTE, ndipo odwala omwe ali pachiwopsezo chachikulu amakhala pabedi kwa nthawi yayitali, atagonekedwa, osayenda, ndikuyikidwa pazida zosiyanasiyana. Njira zochizira monga machubu nazonso ndi zinthu zomwe zimayambitsa thrombosis. Chifukwa chake, kwa odwala omwe ali pachiwopsezo chachikulu komanso omwe ali pachiwopsezo chachikulu, kupewa VTE mwamakina, monga masokisi otambalala, pampu yopumira mpweya, ndi zina zotero, zitha kuchitidwa; nthawi yomweyo, mbiri yakale ya matenda a wodwalayo iyenera kumvedwa bwino, ndipo ntchito ya wodwalayo yolimbitsa magazi iyenera kuyesedwa nthawi yake. Kwa odwala, njira yopewera magazi oletsa magazi kutsekeka ikhoza kuyambika ngati palibe zotsutsana.

Zotsatira zaposachedwa zikusonyeza kuti matenda otsekeka kwa magazi m'thupi amapezeka kwambiri mwa odwala a COVID-19 omwe ali ndi vuto lalikulu, odwala kwambiri, komanso omwe akumwalira. Kuchuluka kwa ma platelet, DD ndi PT kumagwirizana ndi kuopsa kwa matenda ndipo kungagwiritsidwe ntchito ngati zizindikiro zoyambirira za kuwonongeka kwa matenda panthawi yogona m'chipatala.