Xyoo 2019 tus kab mob coronavirus tshiab (COVID-19) tau kis thoob plaws ntiaj teb. Cov kev tshawb fawb yav dhau los tau qhia tias kev kis tus kab mob coronavirus tuaj yeem ua rau muaj teeb meem coagulation, feem ntau yog tshwm sim los ntawm lub sijhawm ntev ntawm activated partial thromboplastin (APTT), thrombocytopenia, D-dimer (DD). Cov theem siab thiab disseminated intravascular coagulation (DIC), uas cuam tshuam nrog kev tuag ntau dua.

Tsis ntev los no, kev tshuaj xyuas meta-kev ua haujlwm ntawm cov ntshav coagulation hauv cov neeg mob uas muaj COVID-19 (suav nrog 9 txoj kev tshawb fawb rov qab nrog tag nrho 1 105 tus neeg mob) tau qhia tias piv rau cov neeg mob me me, cov neeg mob COVID-19 hnyav muaj cov nqi DD siab dua, lub sijhawm Prothrombin (PT) ntev dua; DD nce ntxiv yog qhov ua rau muaj kev pheej hmoo thiab ua rau muaj kev pheej hmoo tuag. Txawm li cas los xij, Meta-kev tshuaj xyuas saum toj no suav nrog kev tshawb fawb tsawg dua thiab suav nrog cov ntsiab lus tshawb fawb tsawg dua. Tsis ntev los no, ntau qhov kev tshawb fawb loj dua ntawm kev ua haujlwm ntawm cov ntshav coagulation hauv cov neeg mob uas muaj COVID-19 tau tshaj tawm, thiab cov yam ntxwv ntawm cov ntshav coagulation ntawm cov neeg mob uas muaj COVID-19 tau tshaj tawm hauv ntau txoj kev tshawb fawb kuj tsis yog qhov tseeb.

Ib txoj kev tshawb fawb tsis ntev los no raws li cov ntaub ntawv hauv tebchaws tau qhia tias 40% ntawm cov neeg mob COVID-19 muaj feem yuav mob venous thromboembolism (VTE), thiab 11% ntawm cov neeg mob uas muaj feem yuav mob hnyav tsis muaj kev tiv thaiv. VTE. Cov txiaj ntsig ntawm lwm txoj kev tshawb fawb kuj tau qhia tias 25% ntawm cov neeg mob COVID-19 hnyav tau mob VTE, thiab tus nqi tuag ntawm cov neeg mob VTE yog siab txog 40%. Nws qhia tau tias cov neeg mob COVID-19, tshwj xeeb tshaj yog cov neeg mob hnyav lossis mob hnyav, muaj feem yuav mob VTE ntau dua. Qhov laj thawj yog tias cov neeg mob hnyav thiab mob hnyav muaj ntau yam kab mob hauv qab, xws li keeb kwm ntawm kev mob hlwb thiab mob qog nqaij hlav, uas yog txhua yam ua rau muaj VTE, thiab cov neeg mob hnyav thiab mob hnyav tau pw hauv txaj ntev, pw tsaug zog, tsis txav, thiab muab tso rau ntawm ntau yam khoom siv. Kev kho mob xws li cov raj kuj yog cov yam ua rau mob thrombosis. Yog li ntawd, rau cov neeg mob COVID-19 hnyav thiab mob hnyav, kev tiv thaiv kev siv tshuab ntawm VTE, xws li cov thom khwm elastic, lub twj tso kua mis tsis tu ncua, thiab lwm yam, tuaj yeem ua tau; tib lub sijhawm, tus neeg mob keeb kwm kev kho mob yav dhau los yuav tsum nkag siab tag nrho, thiab tus neeg mob txoj kev ua haujlwm coagulation yuav tsum tau soj ntsuam raws sijhawm. ntawm cov neeg mob, kev tiv thaiv anticoagulation tuaj yeem pib yog tias tsis muaj kev tsis sib haum xeeb.

Cov txiaj ntsig tam sim no qhia tau hais tias cov teeb meem coagulation feem ntau tshwm sim rau cov neeg mob COVID-19 hnyav, mob hnyav, thiab tuag. Cov lej platelet, DD thiab PT tus nqi muaj feem cuam tshuam nrog qhov hnyav ntawm tus kab mob thiab tuaj yeem siv ua cov cim qhia ntxov ntawm kev puas tsuaj ntawm tus kab mob thaum lub sijhawm pw hauv tsev kho mob.