I-D-Dimer njengesibonakaliso sokubikezela izifo ezahlukahlukene:

Ngenxa yobudlelwano obuseduze phakathi kwesistimu yokujiya kwegazi kanye nokuvuvukala, umonakalo we-endothelial, kanye nezinye izifo ezingezona eze-thrombotic ezifana nokutheleleka, ukuhlinzwa noma ukulimala, ukwehluleka kwenhliziyo, kanye nezimila eziyingozi, ukwanda kwe-D-Dimer kuvame ukubonwa. Ocwaningweni, kutholakale ukuthi isibikezelo esibi esivame kakhulu salezi zifo kuseyi-thrombosis, i-DIC, njll. Iningi lalezi zinkinga yizifo noma izimo ezihlobene kakhulu ezibangela ukuphakama kwe-D-Dimer. Ngakho-ke i-D-Dimer ingasetshenziswa njengesibonakaliso sokuhlola esibanzi nesibucayi sezifo.

1. Ezigulini ezinomdlavuza, izifundo eziningi zithole ukuthi izinga lokusinda kweminyaka eyi-1-3 leziguli ezine-tumor ebulalayo ezine-D-Dimer ephezulu liphansi kakhulu kunelalabo abane-D-Dimer evamile. I-D-Dimer ingasetshenziswa njengesibonakaliso sokuhlola ukubikezela kweziguli ezine-tumor ebulalayo.

2. Ezigulini ze-VTE, izifundo eziningi ziqinisekisile ukuthi iziguli ezine-D-Dimer ngesikhathi sokuvimbela ukujiya kwegazi zinomngcipheko ophindwe kabili noma kathathu wokuphinda kwe-thrombotic okulandelayo uma kuqhathaniswa neziguli ezingezinhle. Okunye ukuhlaziywa kwe-meta kwabahlanganyeli abangu-1818 ezifundweni ezi-7 kubonise ukuthi i-D-Dimer engavamile ingenye yezibikezelo eziyinhloko zokuphinda kwe-thrombotic ezigulini ze-VTE, futhi i-D-Dimer ifakiwe kumamodeli amaningi okubikezela ingozi yokuphinda kwe-VTE.

3. Ezigulini ezithathelwa indawo yokushintshana kwe-valve yemishini (i-MHVR), ucwaningo lokulandelela isikhathi eside lwabahlanganyeli abangu-618 lubonise ukuthi iziguli ezinamazinga e-D-Dimer angajwayelekile ngesikhathi se-warfarin ngemva kwe-MHVR zazinengozi yezehlakalo ezimbi cishe izikhathi ezi-5 eziphakeme kunalezo ezinamazinga ajwayelekile. Ukuhlaziywa kokuxhumana kwe-Multivariate kuqinisekisile ukuthi amazinga e-D-Dimer ayeyizibikezelo ezizimele ze-thrombosis noma izehlakalo zenhliziyo ngesikhathi sokuvimbela ukuminyana kwegazi.

4. Ezigulini ezine-atrial fibrillation (AF), i-D-Dimer ingabikezela izehlakalo ze-thrombotic kanye nezenhliziyo ngesikhathi sokuvimbela ukujiya kwegazi ngomlomo. Ucwaningo oluzayo lweziguli ezingu-269 ezine-atrial fibrillation olulandelwe iminyaka engaba ngu-2 lubonise ukuthi ngesikhathi sokuvimbela ukujiya kwegazi ngomlomo, cishe ama-23% eziguli ezihlangabezane nezinga le-INR zibonise amazinga e-D-Dimer angajwayelekile, kuyilapho iziguli ezinezinga le-D-Dimer elingajwayelekile zazinengozi ephakeme ngokuphindwe ka-15.8 kanye no-7.64 yezehlakalo ze-thrombotic kanye nezenhliziyo ezihambisana nazo uma kuqhathaniswa neziguli ezinezinga le-D-Dimer elijwayelekile, ngokulandelana.
Kulezi zifo noma iziguli ezithile, i-D-Dimer ephezulu noma ehlala ikhona ivame ukukhombisa ukubikezela okubi noma ukuba kubi kwesimo.