D-Dimer ngati chizindikiro cha matenda osiyanasiyana:

Chifukwa cha ubale wapamtima pakati pa coagulation system ndi kutupa, kuwonongeka kwa endothelial, ndi matenda ena omwe si a thrombotic monga matenda, opaleshoni kapena kuvulala, kulephera kwa mtima, ndi zotupa zowopsa, kuwonjezeka kwa D-Dimer nthawi zambiri kumawonedwa.Mu kafukufuku, anapeza kuti ambiri chokhwima prognosis matenda amenewa akadali thrombosis, DIC, etc. Ambiri mwa mavuto amenewa ndi ndendende matenda ofala kwambiri kapena limati chifukwa D-Dimer kukwera.Chifukwa chake D-Dimer atha kugwiritsidwa ntchito ngati chizindikiro chowunikira komanso chowunikira matenda.

1.Kwa odwala khansa, kafukufuku wambiri apeza kuti kupulumuka kwa zaka 1-3 kwa odwala chotupa choopsa omwe ali ndi D-Dimer okwera ndi otsika kwambiri kuposa omwe ali ndi D-Dimer yachibadwa.D-Dimer ingagwiritsidwe ntchito ngati chizindikiro chowunikira odwala omwe ali ndi chotupa choyipa.

2.Kwa odwala a VTE, kafukufuku wambiri watsimikizira kuti odwala D-Dimer abwino panthawi ya anticoagulation ali ndi chiopsezo chachikulu cha 2-3 chotsatira chotsatira cha thrombotic poyerekeza ndi odwala oipa.Kufufuza kwina kwa anthu a 1818 m'maphunziro a 7 kunasonyeza kuti D-Dimer yosadziwika bwino ndi imodzi mwazomwe zimayambitsa kubwereza kwa thrombotic kwa odwala a VTE, ndipo D-Dimer yaphatikizidwa mu zitsanzo zambiri zolosera za VTE.

3.Kwa odwala omwe amapita ku mechanical valve replacement (MHVR), kufufuza kwa nthawi yaitali kwa anthu 618 kunasonyeza kuti odwala omwe ali ndi matenda a D-Dimer osadziwika panthawi ya warfarin pambuyo pa MHVR anali ndi chiopsezo cha zochitika zovuta za 5 nthawi zambiri kuposa zomwezo. ndi milingo yabwinobwino.Kusanthula kwamalumikizidwe ambiri kunatsimikizira kuti milingo ya D-Dimer inali yodziyimira payokha ya thrombosis kapena zochitika zamtima pa anticoagulation.

4.Kwa odwala atrial fibrillation (AF), D-Dimer akhoza kuneneratu zochitika za thrombotic ndi mtima pa nthawi ya anticoagulation pamlomo.Kafukufuku woyembekezeredwa wa odwala 269 omwe adatsatiridwa kwa zaka pafupifupi 2 adawonetsa kuti panthawi ya anticoagulation pakamwa, pafupifupi 23% ya odwala omwe adakumana ndi mulingo wa INR adawonetsa milingo ya D-Dimer yachilendo, pomwe odwala omwe ali ndi D-Dimer yodwala anali ndi 15.8 ndi Chiwopsezo chowonjezereka cha 7.64 cha zochitika zamtima komanso zofananira zamtima poyerekeza ndi odwala omwe ali ndi milingo yodziwika bwino ya D-Dimer, motsatana.
Kwa matenda kapena odwala awa, D-Dimer yokwezeka kapena yosalekeza nthawi zambiri imawonetsa kusazindikira bwino kapena kuwonjezereka kwa matendawa.