Izinto Eziyisithupha Zizothinta Imiphumela Yokuhlolwa Kwe-Coagulation


Umbhali: Olandelayo   

1. Imikhuba yokuphila

Ukudla (okufana nesibindi sesilwane), ukubhema, ukuphuza, njll. nakho kuzothinta ukutholwa;

2. Imiphumela Yezidakamizwa

(1) I-Warfarin: ithinta kakhulu amanani e-PT kanye ne-INR;
(2) I-Heparin: Ithinta kakhulu i-APTT, engakwazi ukunwetshwa izikhathi ezingu-1.5 kuya kwezi-2.5 (ezigulini eziphathwa ngezidakamizwa ze-anticoagulant, zama ukuqoqa igazi ngemva kokuncishiswa kokuhlushwa kwezidakamizwa noma umuthi usudlule uhhafu wokuphila);
(3) Ama-antibiotics: Ukusetshenziswa kwemithamo emikhulu yama-antibiotic kungabangela ukwanda kwe-PT ne-APTT.Kubikwe ukuthi lapho okuqukethwe kwe-penicillin kufinyelela ku-20,000 u/ML egazini, i-PT ne-APTT ingandiswa izikhathi ezingaphezu kwe-1, futhi inani le-INR lingandiswa izikhathi ezingaphezu kwe-1 (Izimo zokuhlangana okungavamile okubangelwa i-intravenous). I-nodoperazone-sulbactam iye yabikwa)
(4) Izidakamizwa zethrombolytic;
(5) Izidakamizwa ze-emulsion zamafutha ezivela kwamanye amazwe zingaphazamisa imiphumela yokuhlolwa, futhi i-centrifugation yesivinini esiphezulu ingasetshenziswa ukunciphisa ukuphazamiseka esimweni samasampula egazi e-lipid;
(6) Izidakamizwa ezifana ne-aspirin, i-dipyridamole ne-ticlopidine zingavimbela ukuhlangana kweplatelet;

3. Izici zokuqoqwa kwegazi:

(1) Isilinganiso se-sodium citrate anticoagulant egazini ngokuvamile singu-1:9, futhi sixutshwe kahle.Kubikwe ezincwadini ukuthi ukwanda noma ukuncipha kokuhlushwa kwe-anticoagulant kunomthelela ekutholweni kokusebenza kwe-coagulation.Lapho umthamo wegazi ukhuphuka ngo-0.5 mL, isikhathi sokujiya singafinyezwa;lapho umthamo wegazi wehla ngo-0.5 mL, isikhathi sokujiya singandiswa;
(2) Shaya isikhonkwane ekhanda ukuze uvimbele ukulimala kwezicubu kanye nokuxubana kwezici eziphuma ngaphandle;
(3) Isikhathi se-cuff akufanele sidlule i-1 min.Uma i-cuff icindezelwe iqine kakhulu noma isikhathi siside kakhulu, i-factor VIII kanye ne-activator ye-plasmin source yezicubu (t-pA) zizokhishwa ngenxa yokuxhunywa, futhi umjovo wegazi uzoba namandla kakhulu.Kuphinde kube ukuwohloka kwamangqamuzana egazi okwenza kusebenze uhlelo lwe-coagulation.

4. Isikhathi nezinga lokushisa lokubekwa kwesifanekiso:

(1) Izinto zokuhlanganisa Ⅷ kanye Ⅴ azinzile.Njengoba isikhathi sokugcina sikhula, izinga lokushisa lokulondoloza liyakhula, futhi umsebenzi we-coagulation uyanyamalala kancane kancane.Ngakho-ke, i-specimen ye-coagulation yegazi kufanele ithunyelwe ukuze ihlolwe phakathi nehora elingu-1 ngemuva kokuqoqwa, futhi ukuhlolwa kufanele kuqedwe kungakapheli amahora angu-2 ukugwema ukubangela i-PT., ukwelulwa kwe-APTT.(2) Ngezibonelo ezingakwazi ukutholwa ngesikhathi, i-plasma kufanele ihlukaniswe futhi igcinwe ngaphansi kwesivalo futhi ifakwe efrijini ku-2 ℃ ~ 8 ℃.

5. Izibonelo ze-hemolysis emaphakathi/enzima kanye ne-lipidemia

Amasampula e-Hemolyzed anomsebenzi wokuhlangana ofana ne-platelet factor III, engafinyeza isikhathi se-TT, PT, ne-APTT se-plasma ene-hemolyzed futhi yehlise okuqukethwe kwe-FIB.

6. Abanye

I-Hypothermia, i-acidosis, kanye ne-hypocalcemia ingabangela izici ze-thrombin kanye ne-coagulation ukuthi zingasebenzi.