D-Dimer sechiratidzo chekufanotaura kwezvirwere zvakasiyana-siyana:

Nekuda kwehukama hwepedyo huripo pakati pema "coagulation system" nekuzvimba, kukuvara kwe "endothelial", nezvimwe zvirwere zvisina thrombosis zvakaita sehutachiona, kuvhiyiwa kana kukuvara, kutadza kwemoyo, uye bundu rakaipa, kuwedzera kweD-Dimer kunowanzoonekwa. Mukutsvaga, zvakaonekwa kuti fungidziro yakaipa yezvirwere izvi ichiri thrombosis, DIC, nezvimwewo. Mazhinji ematambudziko aya ndiwo chaiwo anowanzo enderana nezvirwere kana mamiriro anokonzera kuwedzera kweD-Dimer. Saka D-Dimer inogona kushandiswa sechiratidzo chakakura uye chinonzwisisika chekuongorora zvirwere.

1. Kune varwere vegomarara, ongororo dzakawanda dzakawana kuti huwandu hwekurarama kwemakore 1-3 hwevarwere vane gomarara rakawanda vane D-Dimer yakakwira hwakaderera zvakanyanya pane hweavo vane D-Dimer yakajairika. D-Dimer inogona kushandiswa sechiratidzo chekuongorora kufambira mberi kwevarwere vane gomarara rakaipa.

2. Kune varwere veVTE, zvidzidzo zvakawanda zvakasimbisa kuti varwere vane D-Dimer panguva yekudzivirira ropa kuvhara vane mukana wakapetwa kaviri kana katatu wekudzoka kweropa mushure mechirwere ichi zvichienzaniswa nevarwere vasina chirwere ichi. Imwe ongororo yekuongorora yakaitwa nevanhu 1818 muzvidzidzo zvinomwe yakaratidza kuti D-Dimer isina kujairika ndeimwe yezviratidzo zvikuru zvekudzoka kweropa muvarwere veVTE, uye D-Dimer yakabatanidzwa mumhando dzakawanda dzekufanotaura njodzi yekudzoka kweropa muVTE.

3. Kune varwere vari kutsiva mavharuvhu emuchina (MHVR), ongororo yekutevera kwenguva refu yevanhu 618 yakaratidza kuti varwere vane huwandu husina kujairika hweD-Dimer panguva yewarfarin mushure meMHVR vaive nenjodzi yezviitiko zvakaipa zvakapetwa ka5 pane avo vane huwandu hwakajairika. Kuongororwa kweMultivariate correlation kwakaratidza kuti huwandu hweD-Dimer hwaive hwakazvimirira hunoratidza thrombosis kana zviitiko zvemwoyo panguva yekudzivirira ropa kupwanya ropa.

4. Kune varwere vane atrial fibrillation (AF), D-Dimer inogona kufanotaura zviitiko zvethrombosis uye zvemwoyo panguva yekurapa ropa rinovhara ropa. Ongororo yakaitwa pavarwere 269 vane atrial fibrillation yakateverwa kwemakore maviri yakaratidza kuti panguva yekurapa ropa rinovhara ropa, vanenge 23% vevarwere vakasangana neINR standard vakaratidza mazinga eD-Dimer asina kujairika, nepo varwere vane mazinga eD-Dimer asina kujairika vaiva nengozi yakakura ka15.8 uye ka7.64 yezviitiko zvethrombosis uye zvemwoyo zvinoenderana nazvo zvichienzaniswa nevarwere vane mazinga eD-Dimer akajairwa, zvichiteerana.
Kune varwere kana zvirwere izvi, kuwedzera kana kuramba uine D-Dimer kunowanzo ratidza kusabudirira kana kuipa kwechirwere.