ʻO D-Dimer ma ke ʻano he hōʻailona prognostic no nā maʻi like ʻole:

Ma muli o ka pilina pili loa ma waena o ka ʻōnaehana coagulation a me ka mumū, ka hōʻino ʻana o ka endothelial, a me nā maʻi ʻē aʻe ʻaʻole thrombotic e like me ka maʻi, ke ʻoki kino a i ʻole ka trauma, ka hāʻule ʻana o ka puʻuwai, a me nā puʻupuʻu malignant, ʻike pinepine ʻia ka piʻi ʻana o D-Dimer. I ka noiʻi ʻana, ua ʻike ʻia ʻo ka prognosis maikaʻi ʻole maʻamau no kēia mau maʻi he thrombosis, DIC, a pēlā aku. ʻO ka hapa nui o kēia mau pilikia ʻo ia nā maʻi pili maʻamau a i ʻole nā ​​​​kūlana e hoʻonui ai i ka D-Dimer. No laila hiki ke hoʻohana ʻia ʻo D-Dimer ma ke ʻano he hōʻailona loiloi ākea a koʻikoʻi no nā maʻi.

1. No nā poʻe maʻi kanesa, ua ʻike ʻia he nui nā noiʻi he haʻahaʻa loa ka nui o ke ola ʻana o nā poʻe maʻi ʻaʻai me ka D-Dimer kiʻekiʻe no 1-3 mau makahiki ma mua o ka poʻe me ka D-Dimer maʻamau. Hiki ke hoʻohana ʻia ka D-Dimer ma ke ʻano he hōʻailona no ka loiloi ʻana i ka wānana o nā poʻe maʻi ʻaʻai.

2. No nā poʻe maʻi VTE, ua hōʻoia nā haʻawina he nui he 2-3 mau manawa kiʻekiʻe ka nui o ka pilikia o ka hoʻi hou ʻana o ka thrombotic ma hope o nā poʻe maʻi me ka D-Dimer i ka wā o ka anticoagulation i hoʻohālikelike ʻia me nā poʻe maʻi maikaʻi ʻole. Ua hōʻike ʻia kekahi meta-analysis o 1818 mau mea komo i loko o 7 mau haʻawina ʻo ka maʻamau ʻole o D-Dimer kekahi o nā mea wānana nui o ka hoʻi hou ʻana o ka thrombotic i nā poʻe maʻi VTE, a ua hoʻokomo ʻia ʻo D-Dimer i loko o nā hiʻohiʻona wānana pilikia VTE recurrence he nui.

3. No nā poʻe maʻi e hana ana i ka hoʻololi valve mechanical (MHVR), ua hōʻike ʻia kahi noiʻi hahai lōʻihi o 618 mau mea komo he 5 mau manawa ka pilikia o nā mea maʻi me nā pae D-Dimer maʻamau ʻole i ka wā warfarin ma hope o MHVR i nā hanana maikaʻi ʻole ma kahi o 5 mau manawa kiʻekiʻe ma mua o ka poʻe me nā pae maʻamau. Ua hōʻoia ka loiloi correlation multivariate he mau wānana kūʻokoʻa nā pae D-Dimer o ka thrombosis a i ʻole nā ​​​​hanana cardiovascular i ka wā anticoagulation.

4. No nā poʻe maʻi me ka atrial fibrillation (AF), hiki i ka D-Dimer ke wānana i nā hanana thrombotic a me nā cardiovascular i ka wā o ka anticoagulation waha. Ua hōʻike ʻia kahi noiʻi e pili ana i 269 mau maʻi me ka atrial fibrillation i ukali ʻia no kahi o 2 mau makahiki i ka wā o ka anticoagulation waha, ma kahi o 23% o nā maʻi i hoʻokō i ke kūlana INR i hōʻike i nā pae D-Dimer maʻamau ʻole, ʻoiai ʻo nā maʻi me nā pae D-Dimer maʻamau he 15.8 a me 7.64 mau manawa kiʻekiʻe aʻe o nā hanana thrombotic a me nā hanana cardiovascular concomitant i hoʻohālikelike ʻia me nā poʻe maʻi me nā pae D-Dimer maʻamau.
No kēia mau maʻi a i ʻole nā ​​​​maʻi kikoʻī, ʻo ka D-Dimer kiʻekiʻe a mau loa paha e hōʻike pinepine ana i ka prognosis maikaʻi ʻole a i ʻole ka hoʻonui ʻia ʻana o ke kūlana.