Ka taea te mōhio mēnā he rerekē te mahi toto toto o te tūroro i mua i te pokanga, ā, ka taea te ārai i ngā āhuatanga ohorere pērā i te toto tonu i te wā e pokanga ana, me muri hoki i te pokanga, kia whiwhi ai i te hua pokanga pai rawa atu.
Ka tutuki te mahi toto-ā-tinana mā te mahi tahi a ngā pereti toto, te pūnaha toto toto, te pūnaha fibrinolytic me te pūnaha endothelial vascular. I mua, i whakamahia e mātou te wā toto hei whakamātautau tirotiro mō ngā hapa mahi toto toto, engari nā te iti o te paerewa, te ngoikore o te aro, me te kore e taea te whakaata i te ihirangi me te mahi a ngā mea toto toto, kua whakakapia e ngā whakamātautau mahi toto toto. Ko ngā whakamātautau mahi toto toto toto ko te wā prothrombin plasma (PT) me te mahi PT i tatauhia mai i te PT, te ōwehenga ā-ao (INR), te fibrinogen (FIB), te wā thromboplastin wāhanga whakahohe (APTT) me te wā thrombin plasma (TT).
Ko te PT te nuinga o te wā e whakaata ana i te mahi a te pūnaha toto toto o waho. Ko te PT roa ka kitea nuitia i roto i te whakahekenga o te take toto toto whānau II, V, VII, me te X, te ngoikore o te fibrinogen, te ngoikore o te take toto toto whiwhi (DIC, te hyperfibrinolysis tuatahi, te jaundice aukati, te ngoikore o te huaora K, me ngā matū anticoagulant i roto i te tohanga toto. Ko te whakapoto o te PT ka kitea nuitia i roto i te pikinga o te take toto toto whānau V, te DIC wawe, ngā mate toto toto, ngā ārai hapū, me ētahi atu; ka taea te whakamahi i te aroturukitanga PT hei aroturukitanga o ngā rongoā anticoagulant waha haumanu.
Ko te APTT te whakamātautau tirotiro pono rawa atu mō te korenga o te take toto toto ā-roto. Ko te APTT roa ka kitea nuitia i roto i te hemophilia, te DIC, te mate ate, me te whakawhiti toto nui ki te peeke. Ko te APTT poto ka kitea nuitia i roto i te DIC, te āhua prothrombotic, me ngā mate thrombotic. Ka taea te whakamahi i te APTT hei tohu aroturuki mō te rongoā heparin.
Ka kitea te roa o te TT i roto i te hypofibrinogenemia me te dysfibrinogenemia, te pikinga o te FDP i roto i te toto (DIC), me te aroaro o ngā matū heparin me te heparinoid i roto i te toto (hei tauira, i te wā e rongoatia ana ki te heparin, te SLE, te mate ate, me ētahi atu).
I mua, i reira tētahi tūroro ohorere i whiwhi whakamātautau taiwhanga i mua i te pokanga, ā, ko ngā hua o te whakamātautau toto toto he roa te PT me te APTT, ā, i whakapaetia he DIC kei roto i te tūroro. I raro i te taunakitanga a te taiwhanga, i whai whakamātautau DIC te tūroro, ā, i puta he hua pai. Kāore he tohu mārama o te DIC. Mena kāore te tūroro i whai whakamātautau toto toto, me te pokanga tika, ka kino ngā hua. He maha ngā raruraru pēnei ka kitea mai i te whakamātautau mahi toto toto, kua roa ake te wā mō te kimi me te rongoā haumanu i ngā mate. Ko te whakamātautau raupapa toto toto he whakamātautau taiwhanga nui mō te mahi toto toto o ngā tūroro, ka taea te kite i te mahi toto toto rerekē i roto i ngā tūroro i mua i te pokanga, ā, me aro nui ki tēnā.
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