Binciken Ayyukan Coagulation na Jini


Marubuci: Magaji   

Yana yiwuwa a san ko majiyyaci yana da aikin coagulation na al'ada kafin a yi masa tiyata, yadda ya kamata ya hana al'amuran da ba zato ba tsammani kamar zubar da jini mara tsayawa a lokacin tiyata da bayan tiyata, don samun mafi kyawun aikin tiyata.

Ayyukan hemostatic na jiki yana cika ta hanyar haɗin gwiwa na platelet, tsarin coagulation, tsarin fibrinolytic da tsarin endothelial na jijiyoyin jini.A baya, mun yi amfani da lokacin zubar da jini a matsayin gwajin gwaji don lahani na aikin hemostatic, amma saboda rashin daidaituwarsa, rashin hankali, da rashin iya nuna abun ciki da ayyukan abubuwan coagulation, an maye gurbin shi da gwaje-gwajen aikin coagulation.Gwajin aikin coagulation galibi sun haɗa da lokacin prothrombin na plasma (PT) da ayyukan PT waɗanda aka ƙididdige su daga PT, daidaitaccen rabo na duniya (INR), fibrinogen (FIB), lokacin thromboplastin da aka kunna (APTT) da lokacin thrombin plasma (TT).

PT yafi nuna aikin tsarin coagulation na waje.An fi ganin PT na tsawon lokaci a cikin nau'in coagulation na haihuwa na II, V, VII, da X ragewa, rashi fibrinogen, rashi factor coagulation (DIC, primary hyperfibrinolysis, obstructive jaundice, bitamin K rashi, da anticoagulant abubuwa a cikin jini wurare dabam dabam. PT shortening ne. akasari ana gani a cikin haɓakar coagulation factor V, farkon DIC, cututtukan thrombotic, maganin hana daukar ciki, da sauransu; ana iya amfani da PT saka idanu azaman sa ido kan magungunan rigakafin cututtukan baka na asibiti.

APTT ita ce mafi ingantaccen gwajin gwaji don rashi abubuwan coagulation na endogenous.Ana ganin APTT na tsawon lokaci a cikin haemophilia, DIC, cutar hanta, da kuma ƙarin ƙarin jini na banki.An gajarta APTT a cikin DIC, yanayin prothrombotic, da cututtukan thrombotic.Ana iya amfani da APTT azaman alamar kulawa don maganin heparin.

Ana ganin tsawaitawar TT a cikin hypofibrinogenemia da dysfibrinogenemia, ƙara yawan FDP a cikin jini (DIC), da kasancewar heparin da abubuwan heparinoid a cikin jini (misali, lokacin maganin heparin, SLE, cutar hanta, da dai sauransu).

Akwai sau ɗaya mai haƙuri na gaggawa wanda ya karɓi gwaje-gwajen dakin gwaje-gwaje na farko, kuma sakamakon gwajin coagulation ya tsawaita PT da APTT, kuma ana zargin DIC a cikin mai haƙuri.A karkashin shawarar dakin gwaje-gwaje, mai haƙuri ya yi jerin gwaje-gwaje na DIC kuma sakamakon ya kasance tabbatacce.Babu bayyanannen alamun alamun DIC.Idan majiyyaci ba shi da gwajin coagulation, da tiyata kai tsaye, sakamakon zai zama bala'i.Yawancin irin waɗannan matsalolin ana iya samun su daga gwajin aikin coagulation, wanda ya sayi ƙarin lokaci don gano asibiti da maganin cututtuka.Gwajin jeri na coagulation wani muhimmin gwajin dakin gwaje-gwaje ne don aikin coagulation na marasa lafiya, wanda zai iya gano aikin coagulation mara kyau a cikin marasa lafiya kafin tiyata, kuma yakamata a ba da kulawa sosai.