Nws muaj peev xwm paub seb tus neeg mob puas muaj qhov txawv txav ntawm coagulation ua ntej kev phais, tiv thaiv kom tsis txhob muaj teeb meem tshwm sim xws li los ntshav tsis nres thaum lub sij hawm thiab tom qab kev phais, kom tau txais cov txiaj ntsig zoo tshaj plaws ntawm kev phais.
Lub cev txoj haujlwm hemostatic yog ua tiav los ntawm kev sib koom tes ntawm platelets, coagulation system, fibrinolytic system thiab vascular endothelial system.Yav dhau los, peb siv lub sij hawm los ntshav raws li kev ntsuam xyuas rau hemostatic kev ua haujlwm tsis xws luag, tab sis vim nws cov qauv qis, tsis muaj kev nkag siab zoo, thiab tsis muaj peev xwm los cuam tshuam cov ntsiab lus thiab kev ua ntawm coagulation yam, nws tau hloov los ntawm coagulation function tests.Kev kuaj ntshav coagulation feem ntau suav nrog plasma prothrombin lub sijhawm (PT) thiab PT kev ua haujlwm suav los ntawm PT, thoob ntiaj teb kev sib piv (INR), fibrinogen (FIB), qhib ib nrab thromboplastin lub sijhawm (APTT) thiab plasma thrombin time (TT).
PT feem ntau qhia txog kev ua haujlwm ntawm extrinsic coagulation system.Ntev PT feem ntau pom nyob rau hauv congenital coagulation factor II, V, VII, thiab X txo, fibrinogen deficiency, tau txais coagulation yam tsis txaus (DIC, thawj hyperfibrinolysis, obstructive jaundice, vitamin K deficiency, thiab anticoagulant tshuaj nyob rau hauv cov ntshav ncig. Feem ntau pom nyob rau hauv congenital coagulation factor V nce, thaum ntxov DIC, thrombotic kab mob, qhov ncauj contraceptives, thiab lwm yam
APTT yog qhov kev ntsuam xyuas txhim khu kev qha tshaj plaws rau endogenous coagulation factor deficiency.Ntev APTT feem ntau pom nyob rau hauv hemophilia, DIC, kab mob siab, thiab kev hloov pauv loj ntawm cov ntshav hauv txhab nyiaj.Shortened APTT feem ntau pom hauv DIC, prothrombotic xeev, thiab kab mob thrombotic.APTT tuaj yeem siv los ua qhov ntsuas ntsuas rau kev kho heparin.
TT ncua ntev yog pom hauv hypofibrinogenemia thiab dysfibrinogenemia, nce FDP hauv cov ntshav (DIC), thiab muaj cov tshuaj heparin thiab heparinoid hauv cov ntshav (xws li, thaum kho heparin, SLE, kab mob siab, thiab lwm yam).
Muaj ib zaug ib tus neeg mob xwm txheej ceev uas tau txais kev kuaj mob ua ntej, thiab cov txiaj ntsig ntawm kev kuaj coagulation tau ntev PT thiab APTT, thiab DIC tau xav tias tus neeg mob.Raws li kev pom zoo ntawm lub chaw kuaj mob, tus neeg mob tau txais kev kuaj DIC thiab cov txiaj ntsig tau zoo.Tsis muaj cov tsos mob pom tseeb ntawm DIC.Yog tias tus neeg mob tsis tau kuaj ntshav coagulation, thiab kev phais ncaj qha, qhov tshwm sim yuav muaj kev puas tsuaj.Muaj ntau yam teeb meem zoo li no tuaj yeem pom los ntawm kev kuaj ntshav coagulation, uas tau yuav ntau lub sijhawm rau kev kuaj xyuas thiab kho cov kab mob.Kev sim coagulation series yog ib qho tseem ceeb hauv kev sim rau cov neeg mob cov kev ua haujlwm coagulation, uas tuaj yeem kuaj pom cov coagulation txawv txav hauv cov neeg mob ua ntej kev phais, thiab yuav tsum tau them nyiaj txaus.
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