Ọ ga-ekwe omume ịmara ma onye ọrịa ahụ nwere ọrụ coagulation na-adịghị mma tupu ịwa ahụ, gbochie nke ọma ọnọdụ ndị a na-atụghị anya ya dị ka ọbara ọgbụgba na-adịghị akwụsị n'oge na mgbe ịwachara ahụ, iji nweta mmetụta ịwa ahụ kachasị mma.
A na-arụ ọrụ hemostatic nke ahụ site na njikọta nke platelet, sistemu coagulation, sistem fibrinolytic na sistem endothelial vaskụla.N'oge gara aga, anyị na-eji oge ọbara ọgbụgba dị ka nyocha nyocha maka mmebi ọrụ hemostatic, ma n'ihi nhazi ya dị ala, adịghị ike na-adịghị mma, na enweghị ike igosipụta ọdịnaya na ọrụ nke ihe ndị na-akpata coagulation, ejirila nyocha ọrụ coagulation dochie ya.Nnwale ọrụ coagulation na-agụnye oge prothrombin plasma (PT) na ọrụ PT gbakọrọ site na PT, International normalized ratio (INR), fibrinogen (FIB), oge thromboplastin na-arụ ọrụ (APTT) na oge thrombin plasma (TT).
PT na-egosipụtakarị ọrụ nke sistemu coagulation extrinsic.A na-ahụta PT ogologo oge na congenital coagulation factor II, V, VII, na X mbelata, ụkọ fibrinogen, enwetara ụkọ coagulation factor (DIC, primary hyperfibrinolysis, obstructive jaundice, vitamin K erughi, na anticoagulant bekee na mgbasa ọbara. PT shortening bụ. A na-ahụta nke ọma na mmụba nke coagulation nke mkpụrụ ndụ ihe nketa V, mmalite DIC, ọrịa thrombotic, ọgwụ mgbochi ọnụ, wdg; enwere ike iji PT nleba anya dị ka nyocha nke ọgwụ mgbochi ọnụ nke ụlọ ọgwụ.
APTT bụ ule nyocha kachasị ntụkwasị obi maka ụkọ ihe coagulation endogenous.A na-ahụkarị APTT ogologo oge na hemophilia, DIC, ọrịa imeju, na mmịnye ọbara buru ibu.A na-ahụkarị APTT mkpụmkpụ na DIC, steeti prothrombotic, na ọrịa thrombotic.Enwere ike iji APTT dị ka ihe nleba anya maka ọgwụgwọ heparin.
A na-ahụ ogologo oge TT na hypofibrinogenemia na dysfibrinogenemia, ụbara FDP na ọbara (DIC), na ọnụnọ nke heparin na heparinoids n'ime ọbara (dịka ọmụmaatụ, n'oge ọgwụgwọ heparin, SLE, ọrịa imeju, wdg).
Enwere otu onye ọrịa mberede nke natara ule ụlọ nyocha tupu ịwa ahụ, na nsonaazụ nke ule coagulation na-agbatị ogologo oge PT na APTT, a na-enyo DIC na onye ọrịa ahụ.N'okpuru nkwenye nke ụlọ nyocha, onye ọrịa ahụ nwetara usoro nyocha nke DIC na nsonaazụ ya dị mma.Enweghị akara ngosi doro anya nke DIC.Ọ bụrụ na onye ọrịa enweghị ule coagulation, yana ịwa ahụ ozugbo, nsonaazụ ga-abụ ọdachi.Enwere ike ịchọta ọtụtụ nsogbu dị otú ahụ site na nyocha ọrụ coagulation, nke zụtara oge maka nchọpụta ụlọ ọgwụ na ọgwụgwọ ọrịa.Nnwale usoro coagulation bụ ule ụlọ nyocha dị mkpa maka ọrụ coagulation nke ndị ọrịa, nke nwere ike ịchọpụta ọrụ coagulation na-adịghị mma n'ime ndị ọrịa tupu ịwa ahụ, na ekwesịrị ka etinye ya nke ọma.
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