Yana yiwuwa a san ko majiyyaci yana da aikin toshewar jini na rashin daidaituwa kafin a yi masa tiyata, sannan a hana shi faruwar yanayi na bazata kamar zubar jini ba tare da tsayawa ba yayin da kuma bayan tiyatar, don samun mafi kyawun sakamako na tiyata.
Aikin hemostatic na jiki yana cika ta hanyar haɗin gwiwar platelets, tsarin coagulation, tsarin fibrinolytic da tsarin jijiyoyin jini. A baya, mun yi amfani da lokacin zubar jini a matsayin gwajin tantance lahani na aikin hemostatic, amma saboda ƙarancin daidaito, rashin jin daɗi, da rashin iya nuna abun ciki da ayyukan abubuwan coagulation, an maye gurbinsa da gwaje-gwajen aikin coagulation. Gwaje-gwajen aikin coagulation galibi sun haɗa da lokacin prothrombin na plasma (PT) da aikin PT da aka ƙididdige daga PT, rabon da aka daidaita na ƙasa da ƙasa (INR), fibrinogen (FIB), lokacin thromboplastin na ɓangare (APTT) da lokacin thrombin na plasma (TT).
PT galibi yana nuna aikin tsarin coagulation na waje. Ana ganin PT mai tsawo a cikin raguwar coagulation factor II, V, VII, da X, ƙarancin fibrinogen, ƙarancin coagulation factor da aka samu (DIC, primary hyperfibrinolysis, jaundice mai hana aiki, ƙarancin bitamin K, da abubuwan hana ɗaukar jini a cikin zagayawar jini. Rage PT galibi ana ganinsa ne a cikin ƙaruwar coagulation factor V na haihuwa, DIC na farko, cututtukan thrombotic, magungunan hana ɗaukar ciki ta baki, da sauransu; ana iya amfani da PT a matsayin sa ido kan magungunan hana ɗaukar jini ta baki na asibiti.
APTT ita ce gwajin tantancewa mafi inganci don ƙarancin abubuwan da ke haifar da coagulation na ciki. Ana ganin APTT mai tsawo a cikin hemophilia, DIC, cututtukan hanta, da kuma yawan zubar jini da aka yi a cikin jini. Ana ganin APTT mai gajarta galibi a cikin DIC, yanayin prothrombotic, da cututtukan thrombotic. Ana iya amfani da APTT a matsayin alamar sa ido don maganin heparin.
Ana ganin tsawaita TT a cikin hypofibrinogenemia da dysfibrinogenemia, ƙaruwar FDP a cikin jini (DIC), da kasancewar abubuwan heparin da heparinoid a cikin jini (misali, yayin maganin heparin, SLE, cutar hanta, da sauransu).
Akwai wani majiyyaci na gaggawa da ya sami gwaje-gwajen dakin gwaje-gwaje kafin tiyata, kuma sakamakon gwajin coagulation ya kasance na tsawon lokaci na PT da APTT, kuma ana zargin DIC a cikin majiyyaci. A ƙarƙashin shawarar dakin gwaje-gwaje, majiyyaci ya yi gwaje-gwajen DIC kuma sakamakon ya kasance tabbatacce. Babu alamun DIC bayyanannu. Idan majiyyaci bai yi gwajin coagulation ba, kuma ba a yi masa tiyata kai tsaye ba, sakamakon zai zama bala'i. Ana iya samun irin waɗannan matsaloli da yawa daga gwajin aikin coagulation, wanda ya samar da ƙarin lokaci don gano cututtuka a asibiti da kuma magance su. Gwajin jerin coagulation muhimmin gwajin dakin gwaje-gwaje ne don aikin coagulation na marasa lafiya, wanda zai iya gano aikin coagulation mara kyau a cikin marasa lafiya kafin tiyata, kuma ya kamata a ba shi isasshen kulawa.
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