He tohu tino nui te wā prothrombin (PT) hei whakaata i te mahi hanga ate, te mahi rahui, te kaha o te mate me te matapae. I tēnei wā, kua tino kitea te kitenga haumanu o ngā āhuatanga toto totoka, ā, ka whakaratohia he mōhiohio wawe ake, he tika ake hoki i te PT hei aromatawai i te āhua o te mate ate.

Te whakamahinga haumanu o te PT i roto i te mate ate:

E whā ngā huarahi e pūrongohia ai e te taiwhanga te PT: te ōrau mahi prothrombintimePTA (te ōwehenga wā prothrombin PTR) me te ōwehenga whakaōrite ā-ao INR. He rerekē ngā uara tono haumanu o ngā momo e whā.

Ko te uara o te PT i roto i te mate ate: Ko te PT ka whakatauhia e te taumata o te tauwehenga toto IIvX i hangaia e te ate, ā, he mea tino nui tōna tūranga i roto i te mate ate. Ko te tere rerekē o te PT i roto i te hepatitis whakapeka he 10%-15%, ko te hepatitis mau tonu he 15%-51%, ko te cirrhosis he 71%, ā, ko te hepatitis kino he 90%. I roto i ngā paearu tātaritanga o te hepatitis huaketo i te tau 2000, ko te PTA tētahi o ngā tohu o te wāhanga haumanu o ngā tūroro me te hepatitis huaketo. Ko ngā tūroro hepatitis huaketo mau tonu me te PTA ngawari>70%, he 70%-60% ngawari, he 60%-40% kino; cirrhosis me te wāhanga utu PTA>60% wāhanga kore utu PTA<60%; "he mate ate hepatitis kino PTA<40%" I roto i te whakarōpūtanga Child-Pugh, 1 tohu mō te roanga o te PT o te 1~4 hēkona, 2 tohu mō te 4~6 hēkona, 3 tohu mō te >6 hēkona, me ētahi atu tohu e 4 (albumin, bilirubin, ascites, encephalopathy), ka wehea te mahi ate o ngā tūroro he mate ate. Ka wehea ngā rahui ki ngā tohu ABC; kaute MELD (Tauira mō te mate ate wāhanga-mutunga), e whakatau ana i te kaha o te mate i roto i ngā tūroro he mate ate wāhanga-mutunga me te raupapatanga o te whakawhitinga ate, ko te tātai he .8xloge[bilirubin(mg/dl)+11.2xloge(INR)+ 9.6xloge[creatinine (mg/dl]+6.4x (take: biliary, waipiro rānei 0; ētahi atu 1), ko te INR tētahi o ngā tohu e 3.

Ko ngā paearu tātaritanga DIC mō te mate ate ko: Te roa o te PT mō te neke atu i te 5 hēkona, te wā thromboplastin wāhanga whakahohe (APTT) rānei mō te neke atu i te 10 hēkona, te ngohe o te āhuatanga VIII <50% (e hiahiatia ana); He maha ngā wā ka whakamahia te PT me te tatau pereti hei aromatawai i te koiora ate me te pokanga. Ko te auau toto o ngā tūroro, pērā i ngā pereti <50x10°/L, me te roa o te PT e neke atu ana i te tikanga mō te 4 hēkona, he ārai i te koiora ate me te pokanga tae atu ki te whakawhitinga ate. Ka kitea he mahi nui tā te PT i roto i te tātaritanga me te maimoatanga o ngā tūroro he mate ate.