Waqtiga Prothrombin (PT) waa tilmaame aad muhiim u ah si loo muujiyo shaqada isku-darka beerka, shaqada kaydka, darnaanta cudurka iyo saadaasha. Waqtigan xaadirka ah, ogaanshaha kiliinikada ee arrimaha xinjirowga dhiigga ayaa noqday mid dhab ah, waxayna bixin doontaa macluumaad hore iyo mid sax ah marka loo eego PT marka la go'aaminayo xaaladda cudurka beerka.

Isticmaalka kiliinikada ee PT ee cudurka beerka:

Shaybaarku wuxuu PT u soo sheegaa afar siyaabood: boqolkiiba firfircoonida prothrombintimePTA (saamiga waqtiga prothrombin PTR) iyo saamiga caalamiga ah ee caadiga ah ee INR. Afarta qaab waxay leeyihiin qiimayaal codsi caafimaad oo kala duwan.

Qiimaha codsiga PT ee cudurrada beerka: PT waxaa inta badan lagu go'aamiyaa heerka xinjirowga dhiigga ee IIvX oo uu beerku sameeyay, doorkiisana uu ku leeyahay cudurrada beerka ayaa si gaar ah muhiim u ah. Heerka aan caadiga ahayn ee PT ee hepatitis-ka daran wuxuu ahaa 10%-15%, hepatitis-ka daba-dheeraaday wuxuu ahaa 15%-51%, cirrhosis-ku wuxuu ahaa 71%, iyo hepatitis-ka daran wuxuu ahaa 90%. Shuruudaha ogaanshaha ee hepatitis-ka fayraska sannadkii 2000, PTA waa mid ka mid ah tilmaamayaasha heerka kiliinikada ee bukaannada qaba hepatitis-ka fayraska. Bukaannada hepatitis-ka fayraska ee daba-dheeraada ee qaba PTA khafiif ah>70%, dhexdhexaad ah 70%-60%, daran 60%-40%; cirrhosis-ka oo leh heerka PTA ee la magdhabay>60% heerka PTA ee la magdhabay <60%; Cagaarshowga daran ee PTA <40%" Kala soocidda Child-Pugh, 1 dhibic oo loogu talagalay kordhinta PT ee 1 ~ 4s, 2 dhibcood oo loogu talagalay 4 ~ 6s, 3 dhibcood oo loogu talagalay > 6s, oo lagu daray 4 tilmaame oo kale (albumin, bilirubin, ascites, encephalopathy), shaqada beerka ee bukaanada qaba cudurka beerka Kaydka waxaa loo qaybiyaa darajooyinka ABC; Dhibcaha MELD (Qaabka cudurka beerka ee marxaladda ugu dambeysa), kaas oo go'aamiya darnaanta cudurka ee bukaanada qaba cudurka beerka ee marxaladda ugu dambeysa iyo taxanaha tallaalka beerka, qaacidadu waa .8xloge[bilirubin(mg/dl)+11.2xloge(INR)+ 9.6xloge[creatinine (mg/dl]+6.4x (sabab: biliary ama alcohol 0; kale 1), INR waa mid ka mid ah 3 tilmaame.

Shuruudaha ogaanshaha cudurka beerka ee DIC waxaa ka mid ah: Kordhinta PT in ka badan 5 ilbiriqsi ama waqtiga thromboplastin ee firfircoon (APTT) in ka badan 10 ilbiriqsi, dhaqdhaqaaqa factor VIII <50% (loo baahan yahay); Tirada PT iyo platelet-ka ayaa badanaa loo isticmaalaa in lagu qiimeeyo biopsy-ga beerka iyo qalliinka. U janjeera dhiigbaxa bukaanada, sida platelets-ka <50x10°/L, iyo dheereynta PT oo ka badan heerka caadiga ah ee 4 ilbiriqsi waa arrimo ka hor imaanaya biopsy-ga beerka iyo qalliinka oo ay ku jiraan beerista beerka. Waxaa la arki karaa in PT ay door muhiim ah ka ciyaarto ogaanshaha iyo daaweynta bukaanada qaba cudurka beerka.