Boimana bo tloaelehileng, tlhahiso ea pelo ea eketseha 'me khanyetso ea methapo ea mali ea fokotseha ha lilemo tsa boimana li ntse li eketseha. Ka kakaretso ho lumeloa hore tlhahiso ea pelo ea mali e qala ho eketseha libekeng tse 8 ho isa ho tse 10 tsa boimana, 'me e fihla sehlohlolong libekeng tse 32 ho isa ho tse 34 tsa boimana, e leng 30% ho isa ho 45% ho feta ha motho a sa ima, 'me e boloka boemo bona ho fihlela a pepa. Ho fokotseha ha khanyetso ea methapo ea mali ea methapo ea mali ea methapo ea mali ho fokotsa khatello ea mali ea methapo ea mali, 'me khatello ea mali ea diastolic ea fokotseha haholo, 'me phapang ea khatello ea pelo ea eketseha. Ho tloha libekeng tse 6 ho isa ho tse 10 tsa boimana, bongata ba mali ba basali ba bakhachane boa eketseha ha lilemo tsa boimana li ntse li eketseha, 'me bo eketseha ka hoo e ka bang 40% qetellong ea boimana, empa keketseho ea bongata ba mali ea mali e feta haholo palo ea lisele tse khubelu tsa mali, plasma e eketseha ka 40% ho isa ho 50%, 'me lisele tse khubelu tsa mali li eketseha ka 10% ho isa ho 15%. Ka hona, boimaneng bo tloaelehileng, mali aa hlapolloa, a bonahala e le ho fokotseha ha viscosity ea mali, ho fokotseha ha hematocrit, le ho eketseha ha sekhahla sa sedimentation ea erythrocyte [1].

Mabaka a ho hoama ha mali Ⅱ, Ⅴ, VII, Ⅷ, IX, le Ⅹ kaofela aa eketseha nakong ea boimana, 'me a ka fihla makhetlo a 1.5 ho isa ho a 2.0 a tloaelehileng bohareng le morao ba boimana, 'me mesebetsi ea mabaka a ho hoama ha mali Ⅺ le  ea fokotseha. Fibrinopeptide A, fibrinopeptide B, thrombinogen, platelet factor Ⅳ le fibrinogen li eketsehile haholo, ha antithrombin Ⅲ le protheine C le protheine S li fokotsehile. Nakong ea boimana, nako ea prothrombin le nako ea prothrombin e sa sebetseng e khutsufatsoa, ​​​​'me tekanyo ea fibrinogen ea plasma e eketseha haholo, e ka nyolohelang ho 4-6 g/L karolong ea boraro ea boraro, e leng hoo e ka bang 50% ho feta nakong ea ho se ima. Ho phaella moo, plasminogen e ile ea eketseha, nako ea ho qhibiliha ha euglobulin e ile ea lelefatsoa, ​​​​'me liphetoho tsa ho hoama ha mali le ho thibela ho hoama ha mali li ile tsa etsa hore' mele o be boemong bo matla ba ho hoama ha mali, e leng se ileng sa thusa ho hemostasis e sebetsang ka mor'a ho phatloha ha placenta nakong ea pelehi. Ho phaella moo, mabaka a mang a ka kopanyang mali nakong ea boimana a kenyelletsa keketseho ea k'holeseterole eohle, li-phospholipid le li-triacylglycerols maling, androgen le progesterone tse nkiloeng ke placenta li fokotsa phello ea lithibela-mafu tse itseng tsa mali, placenta, uterine decidua le mahe a embryo. Boteng ba lintho tse nang le thromboplastin, jj., bo ka khothalletsa mali hore a be boemong ba ho kopanya mali haholo, 'me phetoho ena e mpefala ka keketseho ea lilemo tsa boimana. Ho kopanya mali ka mokhoa o itekanetseng ke mokhoa oa tšireletso oa 'mele, o molemo ho boloka fibrin e bolokiloeng methapong ea mali, leboteng la uterine le placental villi, ho thusa ho boloka botšepehi ba placenta le ho theha thrombus ka lebaka la ho hlobola, le ho thusa ho hemostasis e potlakileng nakong ea pelehi le ka mor'a ho pepa. , ke mokhoa oa bohlokoa oa ho thibela ho tsoa mali ka mor'a ho pepa. Ka nako e tšoanang ea ho kopanya mali, ts'ebetso ea bobeli ea fibrinolytic le eona e qala ho tlosa thrombus methapong ea popelo le li-sinuses tsa venous le ho potlakisa tsosoloso le tokiso ea endometrium [2].

Leha ho le jwalo, boemo ba ho hohla ha madi bo ka boela ba baka mathata a mangata a pelehi. Lilemong tsa morao tjena, diphuputso di fumane hore basadi ba bangata ba baimana ba sekametse ho thrombosis. Boemo bona ba lefu la thromboembolism ho basadi ba baimana ka lebaka la diphoso tsa lefutso kapa mabaka a kotsi a fumanehang jwalo ka diprotheine tse thibelang ho hohla madi, mabaka a ho hohla madi, le diprotheine tsa fibrinolytic bo bitswa thrombosis. (thrombophilia), e tsejwang hape e le boemo ba prothrombotic. Boemo bona ba prothrombotic ha bo hlile ha bo lebise lefung la thrombotic, empa bo ka lebisa diphethong tse mpe tsa boimana ka lebaka la ho se leka-lekane ha mekgwa ya ho hohla madi-anticoagulation kapa tshebetso ya fibrinolytic, microthrombosis ya methapo ya popelo ya spiral kapa villus, e leng se fellang ka phallo e mpe ya placental kapa esita le infarction, jwalo ka Preeclampsia, placental abruption, placental infarction, disseminated intravascular coagulation (DIC), thibelo ya kgolo ya lesea, ho senyeheloa ke mpa ho pheta-phetoang, ho tswala ngwana ya shweleng le ho tswala pele ho nako, jj., ho ka lebisa lefung la mme le la pele ho nako maemong a boima.