01. Kuzivana kekutanga naD-dimer, FDP

1. FDP izwi rekuti fibrin nefibrinogen zvinokanganiswa neplasmin, izvo zvinonyanya kuratidza huwandu hwe fibrinolytic hwemuviri;

2. D-dimer chigadzirwa chakasiyana che cross-linked fibrin chinokanganiswa ne plasmin, uye kuwedzera kwehuwandu hwayo kunoratidza kuvapo kwe secondary hyperfibrinolysis;

02. Kushandiswa kweD-dimer neFDP pakurapa

Usabvisa venous thrombosis (VTE inosanganisira DVT, PE)

Kururama kweD-dimer negative exclusion ye deep vein thrombosis (DVT) kunogona kusvika 98%-100%

Kuongororwa kweD-dimer kunogona kushandiswa kubvisa venous thrombosis

♦Kukosha pakuongororwa kweDIC

1. DIC inzira yakaoma yekurapa chirwere ichi uye chirwere chinokonzerwa neropa rakawanda. Mazhinji eDIC anotanga nekukurumidza, chirwere chakaoma, kukura nekukurumidza, kuongororwa kwakaoma, uye kufanotaura kwechirwere ichi kune njodzi. Kana chikasaonekwa nekukurumidza uye chikarapwa zvinobudirira, chinowanzoisa hupenyu hwemurwere panjodzi;

2. D-dimer inogona kuratidza kuoma kweDIC kusvika pamwero wakati, FDP inogona kushandiswa kutarisa kukura kwechirwere mushure mekunge chirwere chasimbiswa, uye antithrombin (AT) inobatsira kunzwisisa kuoma kwechirwere uye kushanda kwekurapa heparin. Kusanganiswa kweD-dimer, FDP neAT bvunzo kwave chiratidzo chakanakisa chekuongorora DIC.

♦Kukosha mumabundu anouraya

1. Matumbu anokuvadza ane chekuita nekushanda zvisina kunaka kwe hemostasis. Pasinei nematumbu akasimba kana leukemia, varwere vachava nemamiriro akaoma ekudzivirira kuungana kweropa kana thrombosis. Adenocarcinoma inokonzereswa ne thrombosis ndiyo inonyanya kuitika;

2. Zvakakosha kusimbisa kuti thrombosis inogona kuva chiratidzo chekutanga chebundu. Muvarwere vane deep vein thrombosis vasingazive zvinhu zvinokonzera thrombosis inobuda ropa, pane mukana wekuti pave nebundu rinogona kuitika.

♦Kukosha kwezvirwere zvevamwe muchipatara

1. Kuongororwa kwekurapwa kwemishonga ye thrombolytic

Munguva yekurapwa, kana huwandu hwemushonga we thrombolytic husina kukwana uye thrombus isina kunyungudika zvachose, D-dimer neFDP zvinoramba zviri padanho repamusoro mushure mekusvika padanho repamusoro; nepo mushonga we thrombolytic wakawandisa unowedzera njodzi yekubuda ropa.

2. Kukosha kwekurapwa kweheparin yemamorekuru madiki mushure mekuvhiyiwa

Varwere vane kukuvara/kuvhiyiwa vanowanzo pihwa mushonga wekudzivirira ropa kubva muropa.

Kazhinji, chiyero chekutanga cheheparin diki i2850IU/zuva, asi kana huwandu hweD-dimer hwemurwere huri 2ug/ml pazuva rechina mushure mekuvhiyiwa, chiyero chinogona kuwedzerwa kusvika kaviri pazuva.

3. Kutsemuka kwetsinga huru yeropa (AAD)

Chirwere cheAAD chinowanzo kukonzera rufu rwechimbichimbi muvarwere. Kuongororwa nekukurumidza uye kurapwa kunogona kuderedza huwandu hwekufa kwevarwere uye kuderedza njodzi dzehutano.

Nzira inogona kushandiswa kuwedzera D-dimer muAAD: Mushure mekunge chikamu chepakati chemadziro etsinga yeaortic chakakuvara nekuda kwezvikonzero zvakasiyana-siyana, madziro etsinga anoputika, zvichiita kuti ropa ripinde mukati nekunze kwemukati kuti rigadzire "gomba renhema", nekuda kweropa rechokwadi nerenhema riri mugomba. Pane musiyano mukuru mukumhanya kwekuyerera, uye kumhanya kwekuyerera mugomba renhema kunononoka, izvo zvinogona kukonzera thrombosis zviri nyore, kukonzera kuti fibrinolytic system ishande, uye pakupedzisira kukurudzira kuwedzera kweD-dimer level.

03. Zvinhu zvinokanganisa D-dimer neFDP

1. Hunhu hwemuviri

Yakakwira: Kune mutsauko mukuru pakati pezera, vakadzi vane pamuviri, maekisesaizi anorema, uye kuenda kumwedzi.

2. Kukanganiswa kwezvirwere

Yakakwira: sitiroko yeropa, kurapwa kweropa, hutachiona hwakakomba, sepsis, gangrene yematishu, preeclampsia, hypothyroidism, chirwere chechiropa chakakomba, sarcoidosis.

3.Kuwedzera kwemafuta mumuviri uye migumisiro yekunwa doro

Yakakwidziridzwa: vanonwa;

Kuderedza: hyperlipidemia.

4. Mhedzisiro yemishonga

Yakakwidziridzwa: heparin, mishonga inoderedza BP, urokinase, streptokinase uye staphylokinase;

Kuderera: mishonga yekudzivirira pamuviri inonwiwa uye estrogen.
04. Pfupiso

Kuonekwa kweD-dimer neFDP kwakachengeteka, kuri nyore, kunokurumidza, hakudhuri, uye kunonyanya kubatwa nechirwere. Zvese izvi zvine mwero wakasiyana wekuchinja kwechirwere chemwoyo, chirwere chechiropa, chirwere chetsinga dzeropa, BP inokonzerwa nepamuviri, uye pre-eclampsia. Zvakakosha kuona kuti chirwere ichi chakanyanya sei, kutarisa kukura kwechirwere ichi nekuchinja kwacho, uye kuongorora mhedzisiro yekurapa.