Koj yuav tsum paub cov no txog D-dimer thiab FDP


Sau: Succeeder   

Thrombosis yog qhov txuas tseem ceeb tshaj plaws uas ua rau lub plawv, lub hlwb thiab cov kab mob peripheral vascular, thiab yog qhov ua rau tuag lossis tsis taus.Yooj yim muab, tsis muaj kab mob plawv tsis muaj thrombosis!

Nyob rau hauv tag nrho cov kab mob thrombotic, venous thrombosis suav txog li 70%, thiab arterial thrombosis suav txog li 30%.Qhov tshwm sim ntawm venous thrombosis yog siab, tab sis tsuas yog 11% -15% tuaj yeem kuaj pom.Feem ntau cov venous thrombosis tsis muaj tsos mob thiab yog ib qho yooj yim kom tsis nco qab los yog kuaj tsis raug.Nws yog lub npe hu ua tus uas ntsiag to killer.

Hauv kev tshuaj xyuas thiab kuaj mob ntawm cov kab mob thrombotic, D-dimer thiab FDP, uas yog cov cim qhia ntawm fibrinolysis, tau nyiam ntau yam vim lawv qhov tseem ceeb hauv kev kho mob.

20211227001

01. Thawj zaug paub nrog D-dimer, FDP

1. FDP yog cov ntsiab lus dav dav rau ntau yam khoom degradation ntawm fibrin thiab fibrinogen nyob rau hauv qhov kev txiav txim ntawm plasmin, uas feem ntau qhia txog tag nrho cov fibrinolytic theem ntawm lub cev;

2. D-dimer yog ib yam khoom degradation ntawm cross-linked fibrin nyob rau hauv qhov kev txiav txim ntawm plasmin, thiab qhov nce ntawm nws qib qhia tau hais tias muaj nyob rau theem nrab hyperfibrinolysis;

02. Kev kho mob ntawm D-dimer thiab FDP

Tsis suav nrog venous thrombosis (VTE suav nrog DVT, PE)

Qhov tseeb ntawm D-dimer tsis suav nrog kev sib sib zog nqus vein thrombosis (DVT) tuaj yeem ncav cuag 98% -100%

Kev kuaj pom D-dimer tuaj yeem siv los txiav txim siab venous thrombosis

♦ Qhov tseem ceeb hauv kev kuaj mob ntawm DIC

1. DIC yog cov txheej txheem pathophysiological nyuaj thiab mob hnyav tau txais kev kho mob thrombo-hemorrhagic syndrome.Feem ntau DICs muaj qhov pib sai, kab mob nyuaj, kev loj hlob sai, kev kuaj mob nyuaj, thiab kev pheej hmoo txaus ntshai.Yog tias tsis kuaj pom ntxov thiab kho tau zoo, Feem ntau ua rau tus neeg mob lub neej txaus ntshai;

2. D-dimer tuaj yeem cuam tshuam qhov hnyav ntawm DIC rau qee qhov, FDP tuaj yeem siv los saib xyuas kev txhim kho ntawm tus kab mob tom qab kuaj pom tseeb, thiab cov tshuaj antithrombin (AT) pab kom nkag siab qhov hnyav ntawm tus kab mob thiab cov txiaj ntsig ntawm Kev kho mob heparin Kev sib xyaw ua ke ntawm D-dimer, FDP thiab AT kuaj tau dhau los ua qhov taw qhia zoo tshaj plaws rau kev kuaj mob DIC.

♦ Qhov tseem ceeb hauv cov qog nqaij hlav

1. Cov qog nqaij hlav qog muaj feem cuam tshuam nrog kev ua haujlwm ntawm hemostasis.Txawm hais tias cov qog nqaij hlav malignant lossis leukemia, cov neeg mob yuav muaj lub xeev hypercoagulable lossis thrombosis.Adenocarcinoma nyuaj los ntawm thrombosis yog feem ntau;

2. Nws yog tsim nyog hais tias thrombosis tej zaum yuav yog ib qho mob thaum ntxov ntawm cov qog.Hauv cov neeg mob uas muaj cov hlab ntsha sib sib zog nqus uas tsis tuaj yeem kuaj pom qhov muaj feem cuam tshuam ntawm cov ntshav thrombosis, yuav muaj cov qog nqaij hlav.

♦ Kev kho mob tseem ceeb ntawm lwm yam kab mob

1. Kev soj ntsuam ntawm kev kho cov tshuaj thrombolytic

Nyob rau hauv cov chav kawm ntawm kev kho mob, yog hais tias tus nqi ntawm cov tshuaj thrombolytic tsis txaus thiab cov thrombus tsis tag yaj, D-dimer thiab FDP yuav tuav ib tug siab theem tom qab mus txog lub ncov;thaum cov tshuaj thrombolytic ntau dhau yuav ua rau muaj kev pheej hmoo los ntshav.

2. Qhov tseem ceeb ntawm me me molecule heparin kho tom qab phais

Cov neeg mob raug mob / phais feem ntau kho nrog anticoagulant prophylaxis.

Feem ntau, cov koob tshuaj me me ntawm cov tshuaj heparin yog 2850IU / d, tab sis yog tias tus neeg mob qib D-dimer yog 2ug / ml nyob rau hnub 4 tom qab kev phais, qhov koob tshuaj tuaj yeem nce mus rau 2 zaug hauv ib hnub.

3. Mob aortic dissection (AAD)

AAD yog ib qho ua rau tuag sai sai rau cov neeg mob.Kev kuaj mob ntxov thiab kev kho mob tuaj yeem txo qhov kev tuag ntawm cov neeg mob thiab txo cov kev pheej hmoo kho mob.

Cov txheej txheem ua tau rau qhov nce ntawm D-dimer hauv AAD: Tom qab cov txheej txheem nruab nrab ntawm cov hlab ntsha aortic puas vim muaj ntau yam laj thawj, cov phab ntsa vascular ruptures, ua rau cov ntshav nkag mus rau sab hauv thiab sab nrauv los tsim "cov kab noj hniav cuav" , vim qhov tseeb thiab tsis tseeb cov ntshav hauv cov kab noj hniav muaj qhov sib txawv loj ntawm qhov khiav ceev, thiab qhov khiav ceev hauv cov kab noj hniav cuav kuj qeeb, uas tuaj yeem ua rau mob thrombosis, ua rau cov kab mob fibrinolytic tau qhib, thiab thaum kawg txhawb nqa. nce qib D-dimer.

03. Yam cuam tshuam rau D-dimer thiab FDP

1. Cov yam ntxwv ntawm lub cev

Siab: Muaj qhov sib txawv ntawm lub hnub nyoog, cov poj niam cev xeeb tub, kev tawm dag zog, kev coj khaub ncaws.

2. Kab mob cuam tshuam

Ua kom siab: cerebrovascular stroke, thrombolytic kho, mob hnyav, sepsis, nqaij gangrene, preeclampsia, hypothyroidism, mob siab heev, sarcoidosis.

3.Hyperlipidemia thiab cov teebmeem ntawm kev haus cawv

Siab: cov neeg haus dej haus cawv;

Txo: hyperlipidemia.

4. Cov teebmeem tshuaj

nce: heparin, tshuaj tiv thaiv hypertensive, urokinase, streptokinase thiab staphylokinase;

Txo: cov tshuaj tiv thaiv qhov ncauj thiab tshuaj estrogen.
04. Cov ntsiab lus

D-dimer thiab FDP kuaj pom muaj kev nyab xeeb, yooj yim, ceev, kev lag luam, thiab muaj kev nkag siab zoo.Ob leeg ntawm lawv yuav muaj ntau yam kev hloov pauv ntawm cov kab mob plawv, kab mob siab, kab mob cerebrovascular, cev xeeb tub vim ntshav siab, thiab pre-eclampsia.Nws yog ib qho tseem ceeb los txiav txim qhov hnyav ntawm tus kab mob, saib xyuas txoj kev loj hlob thiab kev hloov ntawm tus kab mob, thiab ntsuas qhov prognosis ntawm curative nyhuv.nyhuv.