01. Kev paub thawj zaug nrog D-dimer, FDP

1. FDP yog lo lus dav dav rau ntau yam khoom puas tsuaj ntawm fibrin thiab fibrinogen nyob rau hauv qhov kev ua ntawm plasmin, uas feem ntau qhia txog qib fibrinolytic tag nrho ntawm lub cev;

2. D-dimer yog ib qho khoom tawg tshwj xeeb ntawm cov fibrin sib txuas ua ke nyob rau hauv qhov kev ua ntawm plasmin, thiab qhov nce ntawm nws qib qhia tau tias muaj qhov muaj hyperfibrinolysis theem ob;

02. Kev siv tshuaj kho mob ntawm D-dimer thiab FDP

Tsis suav cov kab mob venous thrombosis (VTE suav nrog DVT, PE)

Qhov tseeb ntawm D-dimer tsis zoo tshem tawm ntawm cov hlab ntsha tob tob (DVT) tuaj yeem ncav cuag 98% -100%

Kev kuaj mob D-dimer tuaj yeem siv los txiav txim siab qhov mob ntawm cov hlab ntsha thrombosis

♦Qhov tseem ceeb hauv kev kuaj mob DIC

1. DIC yog ib qho txheej txheem pathophysiological nyuaj thiab mob hnyav heev uas tau txais los ntawm kev kho mob thrombo-hemorrhagic syndrome. Feem ntau DICs muaj kev pib sai, kab mob nyuaj, kev loj hlob sai, kev kuaj mob nyuaj, thiab kev kwv yees txaus ntshai. Yog tias tsis kuaj pom ntxov thiab kho tau zoo, feem ntau yuav ua rau tus neeg mob lub neej muaj kev phom sij;

2. D-dimer tuaj yeem qhia txog qhov hnyav ntawm DIC rau qee qhov, FDP tuaj yeem siv los saib xyuas kev loj hlob ntawm tus kab mob tom qab kuaj pom tseeb, thiab antithrombin (AT) pab nkag siab txog qhov hnyav ntawm tus kab mob thiab qhov ua tau zoo ntawm kev kho mob heparin. Kev sib xyaw ua ke ntawm D-dimer, FDP thiab AT kuaj tau dhau los ua qhov qhia zoo tshaj plaws rau kev kuaj mob DIC.

♦Qhov tseem ceeb hauv cov qog nqaij hlav phem

1. Cov qog nqaij hlav phem muaj feem cuam tshuam nrog kev ua haujlwm ntawm hemostasis. Txawm hais tias cov qog nqaij hlav phem lossis leukemia, cov neeg mob yuav muaj lub xeev hypercoagulable lossis thrombosis. Adenocarcinoma uas nyuaj los ntawm thrombosis yog qhov feem ntau;

2. Nws tsim nyog hais tias qhov mob thrombosis tej zaum yuav yog ib qho tsos mob thaum ntxov ntawm qog nqaij hlav. Rau cov neeg mob uas muaj cov leeg ntshav tob uas tsis pom cov yam txaus ntshai ntawm kev mob thrombosis, tej zaum yuav muaj qog nqaij hlav.

♦Qhov tseem ceeb ntawm kev kho mob ntawm lwm yam kab mob

1. Kev saib xyuas kev kho mob thrombolytic

Thaum lub sijhawm kho mob, yog tias cov tshuaj thrombolytic tsis txaus thiab cov thrombus tsis yaj tag, D-dimer thiab FDP yuav tswj tau qib siab tom qab mus txog qhov siab tshaj plaws; thaum cov tshuaj thrombolytic ntau dhau yuav ua rau muaj kev pheej hmoo ntawm kev los ntshav.

2. Qhov tseem ceeb ntawm kev kho mob me me heparin tom qab phais

Cov neeg mob uas raug mob/phais feem ntau raug kho nrog cov tshuaj anticoagulant prophylaxis.

Feem ntau, cov koob tshuaj heparin me me yog 2850IU/hnub, tab sis yog tias tus neeg mob D-dimer theem yog 2ug/ml rau hnub thib 4 tom qab phais, cov koob tshuaj tuaj yeem nce mus txog 2 zaug hauv ib hnub.

3. Kev txiav cov hlab ntsha loj (AAD)

AAD yog ib qho ua rau cov neeg mob tuag tam sim ntawd. Kev kuaj mob thaum ntxov thiab kev kho mob tuaj yeem txo qhov feem pua ​​​​​​ntawm kev tuag ntawm cov neeg mob thiab txo cov kev pheej hmoo kho mob.

Lub tshuab ua rau D-dimer nce ntxiv hauv AAD: Tom qab txheej nruab nrab ntawm phab ntsa aortic raug puas tsuaj vim ntau yam laj thawj, phab ntsa vascular tawg, ua rau ntshav nkag mus rau sab hauv thiab sab nraud kom tsim tau "qhov chaw cuav", vim yog cov ntshav tseeb thiab cuav hauv qhov chaw muaj qhov sib txawv loj hauv qhov ceev ntws, thiab qhov ceev ntws hauv qhov chaw cuav qeeb qeeb, uas tuaj yeem ua rau thrombosis yooj yim, ua rau lub cev fibrinolytic ua haujlwm, thiab thaum kawg txhawb kev nce ntawm D-dimer theem.

03. Tej yam uas cuam tshuam rau D-dimer thiab FDP

1. Cov yam ntxwv ntawm lub cev

Siab: Muaj qhov sib txawv tseem ceeb hauv hnub nyoog, cov poj niam cev xeeb tub, kev tawm dag zog hnyav, thiab kev muaj hli.

2. Kev cuam tshuam ntawm kab mob

Siab: mob hlwb cerebrovascular, kev kho mob thrombolytic, kev kis kab mob hnyav, sepsis, cov ntaub so ntswg gangrene, preeclampsia, hypothyroidism, kab mob siab hnyav, sarcoidosis.

3. Kab mob ntshav siab thiab cov teebmeem ntawm kev haus dej cawv

Siab: cov neeg haus dej;

Txo: hyperlipidemia.

4. Cov teebmeem ntawm tshuaj

Siab: heparin, tshuaj antihypertensive, urokinase, streptokinase thiab staphylokinase;

Txo: kev tiv thaiv kev xeeb tub thiab estrogen.
04. Cov Lus Qhia Luv Luv

Kev kuaj pom D-dimer thiab FDP muaj kev nyab xeeb, yooj yim, ceev, pheej yig, thiab muaj kev nkag siab zoo heev. Ob leeg yuav muaj ntau qib kev hloov pauv hauv kab mob plawv, kab mob siab, kab mob cerebrovascular, ntshav siab vim cev xeeb tub, thiab pre-eclampsia. Nws yog ib qho tseem ceeb kom txiav txim siab qhov hnyav ntawm tus kab mob, saib xyuas kev loj hlob thiab kev hloov pauv ntawm tus kab mob, thiab ntsuas qhov kev kwv yees ntawm cov txiaj ntsig kho.