01. Sanin farko da D-dimer, FDP

1. FDP kalma ce ta gabaɗaya don samfuran lalacewa daban-daban na fibrin da fibrinogen ƙarƙashin aikin plasmin, wanda galibi yana nuna matakin fibrinolytic na jiki gaba ɗaya;

2. D-dimer wani takamaiman samfurin lalata ne na fibrin mai haɗin gwiwa a ƙarƙashin aikin plasmin, kuma ƙaruwar matakinsa yana nuna wanzuwar hyperfibrinolysis na biyu;

02. Amfani da D-dimer da FDP a asibiti

Banda zubar jini a cikin jijiyoyin jini (VTE ya haɗa da DVT, PE)

Daidaiton cirewar jijiyoyin jini masu zurfi (DVT) daga D-dimer na iya kaiwa kashi 98%-100%

Ana iya amfani da gano D-dimer don kawar da thrombosis na jijiyoyin jini

♦Muhimmanci a cikin ganewar asali na DIC

1. DIC tsari ne mai rikitarwa na cututtukan da ke haifar da cututtukan jijiyoyin jini da kuma mummunan ciwon jijiyoyin jini da ke kama da thrombosis. Yawancin DICs suna da saurin kamuwa da cuta, cututtuka masu rikitarwa, ci gaba cikin sauri, ganewar asali mai wahala, da kuma hasashen haɗari. Idan ba a gano su da wuri ba kuma ba a yi musu magani yadda ya kamata ba, sau da yawa suna sanya rayuwar majiyyaci cikin haɗari;

2. D-dimer na iya nuna tsananin DIC zuwa wani mataki, ana iya amfani da FDP don sa ido kan ci gaban cutar bayan an tabbatar da ganewar cutar, kuma antithrombin (AT) yana taimakawa wajen fahimtar tsananin cutar da ingancin maganin heparin. Haɗin gwajin D-dimer, FDP da AT ya zama mafi kyawun alama don gano DIC.

♦ Muhimmanci a cikin ciwon daji masu cutarwa

1. Ciwon daji mai tsanani yana da alaƙa da rashin aikin hemostasis. Ko da kuwa akwai ciwon daji mai tsanani ko cutar sankarar bargo, marasa lafiya za su sami matsanancin yanayin da ke iya yin coagulable ko thrombosis. Adenocarcinoma mai rikitarwa ta hanyar thrombosis shine mafi yawan lokuta;

2. Ya kamata a jaddada cewa thrombosis na iya zama alamar farko ta ƙari. Ga marasa lafiya da ke fama da thrombosis na jijiyoyin jini waɗanda suka kasa gano abubuwan da ke haifar da zubar jini, akwai yiwuwar samun ƙari.

♦ Muhimmancin asibiti na sauran cututtuka

1. Kula da maganin thrombolytic

A lokacin jiyya, idan adadin maganin thrombolytic bai isa ba kuma thrombus bai narke gaba ɗaya ba, D-dimer da FDP za su ci gaba da kasancewa a matakin da ya dace bayan sun kai kololuwa; yayin da yawan shan maganin thrombolytic zai ƙara haɗarin zubar jini.

2. Muhimmancin maganin ƙananan ƙwayoyin heparin bayan tiyata

Sau da yawa ana yi wa marasa lafiya da suka ji rauni/tiyata magani da rigakafin hana zubar jini.

Gabaɗaya, babban maganin heparin ƙaramin ƙwayar cuta shine 2850IU/rana, amma idan matakin D-dimer na majiyyaci shine 2ug/ml a rana ta 4 bayan tiyata, ana iya ƙara yawan maganin zuwa sau 2 a rana.

3. Ragewar jijiyoyin jini mai tsanani (AAD)

AAD abu ne da ya zama ruwan dare gama gari da ke haifar da mutuwar kwatsam ga marasa lafiya. Gano cutar da wuri da kuma magani na iya rage yawan mace-macen marasa lafiya da kuma rage haɗarin kamuwa da cutar a fannin lafiya.

Tsarin da zai iya ƙara yawan D-dimer a cikin AAD: Bayan tsakiyar layin bangon jijiyoyin jini ya lalace saboda dalilai daban-daban, bangon jijiyoyin jini yana fashewa, yana sa jini ya mamaye layin ciki da waje don samar da "rami na ƙarya", saboda jinin gaskiya da na ƙarya a cikin ramin Akwai babban bambanci a cikin saurin kwarara, kuma saurin kwarara a cikin ramin ƙarya yana da jinkiri kaɗan, wanda zai iya haifar da thrombosis cikin sauƙi, yana sa tsarin fibrinolytic ya kunna, kuma a ƙarshe yana haɓaka ƙaruwar matakin D-dimer.

03. Abubuwan da ke shafar D-dimer da FDP

1. Halayen Halittar Jiki

An ƙara girma: Akwai manyan bambance-bambance a cikin shekaru, mata masu juna biyu, motsa jiki mai ƙarfi, da kuma jinin al'ada.

2. Tasirin cututtuka

Babban: bugun jini na cerebrovascular, maganin thrombolytic, kamuwa da cuta mai tsanani, sepsis, gangrene na nama, preeclampsia, hypothyroidism, cututtukan hanta mai tsanani, sarcoidosis.

3. Yawan kitse a jiki da illolin shan giya

An ɗaga: masu shan giya;

Rage: hyperlipidemia.

4. Tasirin magunguna

An ƙara yawan amfani da shi: heparin, magungunan rage hawan jini, urokinase, streptokinase da staphylokinase;

Ragewa: maganin hana haihuwa ta baki da kuma estrogen.
04. Takaitaccen Bayani

Gano D-dimer da FDP abu ne mai aminci, mai sauƙi, mai sauri, mai araha, kuma mai matuƙar sauƙi. Dukansu za su sami canje-canje daban-daban a cikin cututtukan zuciya da jijiyoyin jini, cututtukan hanta, cututtukan cerebrovascular, hauhawar jini da ciki ke haifarwa, da kuma pre-eclampsia. Yana da mahimmanci a yi la'akari da tsananin cutar, a sa ido kan ci gaba da canjin cutar, sannan a kimanta hasashen tasirin maganin.