Hangata thrombosis e na le maemo a mararo a latelang:

1. Kotsi e haufi-ufi ea pelo le methapo ea mali

Intima ea methapo ea mali e tloaelehileng ea pelo le ea mali e tiile ebile e boreleli, 'me lisele tsa endothelial tse sa senyehang li ka thibela ho khomarela ha platelet le ho thibela ho ruruha ha mali. Ha lera le ka hare le senyehile, tsamaiso ea ho ruruha e ka kenngoa tšebetsong ka litsela tse ngata.

Intima ea pele e senyehileng e lokolla factor ea coagulation ea lisele (coagulation factor III), e kenyang tšebetsong sistimi ea coagulation ea kantle.
Sa bobedi, kamora hore intima e senyehe, disele tsa endothelial di a senyeha, di a tshwaetswa, mme di a tsholoha, di pepesa difaeba tsa collagen tlasa endothelium, ka hona di kenya tshebetsong coagulation factor XII ya sistimi ya endogenous coagulation mme di qala tsamaiso ya endogenous coagulation. Ho feta moo, intima e senyehileng e ba thata, e leng se thusang ho boloka le ho kgomarela diplatelete. Kamora hore diplatelete tse kgomaretsweng di phatlohe, ho lokollwa dintho tse fapaneng tsa platelet, mme tshebetso yohle ya coagulation e a kenngwa tshebetsong, e leng se etsang hore madi a kgomarele mme a thehe thrombus.
Mabaka a fapaneng a 'mele, lik'hemik'hale le a baeloji a ka baka tšenyo ho intima ea pelo le methapo ea mali, joalo ka endocarditis ho li-erysipelas tsa likolobe, vasculitis ea matšoafo ho pneumonia ea likhomo, arteritis ea li-parasitic ea equine, ente e pheta-phetoang karolong e le 'ngoe ea mothapo, Kotsi le ho phunya lebota la mothapo oa mali nakong ea opereishene.

2. Liphetoho boemong ba phallo ea mali

Haholo-holo e bua ka phallo e liehang ea mali, ho thehoa ha vortex le ho khaotsa ho phalla ha mali.
Tlas'a maemo a tloaelehileng, sekhahla sa phallo ea mali se potlakile, 'me lisele tse khubelu tsa mali, li-platelet le likarolo tse ling li bokellana bohareng ba mothapo oa mali, o bitsoang phallo ea axial; ha sekhahla sa phallo ea mali se fokotseha, lisele tse khubelu tsa mali le li-platelet li tla phalla haufi le lebota la mothapo oa mali, o bitsoang phallo ea lehlakore, e eketsang thrombosis.
Phallo ea mali e fokotseha, 'me lisele tsa endothelial li na le hypoxia e ngata, e leng se bakang ho senyeha le ho fela ha lisele tsa endothelial, tahlehelo ea mosebetsi oa tsona oa ho kopanya le ho lokolla lintho tse thibelang ho ruruha ha mali, le ho pepesehela collagen, e kenyang tšebetsong tsamaiso ea ho ruruha le ho khothalletsa thrombosis.
Phallo e liehang ea mali e ka boela ea etsa hore thrombus e entsoeng e be bonolo ho e lokisa leboteng la mothapo oa mali 'me e tsoele pele ho eketseha.

Ka hona, thrombus hangata e hlaha methapong e phallang mali butle le e sekametseng ho phalla ha metsi (li-valve tsa venous). Phallo ea mali ea aortic e potlakile, 'me thrombus ha e bonahale hangata. Ho ea ka lipalo-palo, ho hlaha ha venous thrombosis ho feta makhetlo a 4 ho feta ha arterial thrombosis, 'me venous thrombosis hangata e hlaha ho hloleheng ha pelo, kamora opereishene kapa ho liphoofolo tse kulang tse robetseng sehlaheng nako e telele.
Ka hona, ho bohlokoa haholo ho thusa liphoofolo tse kulang tse robetseng nako e telele le ka mor'a opereishene ho etsa mesebetsi e meng e loketseng ho thibela thrombosis.
3. Liphetoho thepeng ea mali.

Haholo-holo e bua ka keketseho ea ho hoama ha mali. Tse kang ho chesa haholo, ho felloa ke metsi 'meleng, jj. ho bokellana maling, kotsi e kholo, kamora ho pepa, le tahlehelo e kholo ea mali kamora liopereishene tse kholo li ka eketsa palo ea li-platelet maling, tsa eketsa viscosity ea mali, 'me tsa eketsa litaba tsa fibrinogen, thrombin le lintlha tse ling tsa ho hoama maling. Keketseho ea plasma. Lintho tsena li ka khothaletsa thrombosis.