Thrombosis inowanzova nemamiriro matatu anotevera:

1. Mwoyo netsinga dzeropa panguva yekukuvara kwepedyo

Kubatana kwemwoyo netsinga dzeropa zvakanaka hakuna kukanganiswa uye kwakapfava, uye masero e endothelial asina kukanganiswa anogona kudzivirira kunamatira kwemaplatelet uye kudzivirira kuungana kweropa. Kana membrane yemukati yakakuvara, sisitimu yekubatanidza ropa inogona kushanda nenzira dzakawanda.

Intima yekutanga yakakuvara inoburitsa chinhu chinosunga tissue (coagulation factor III), iyo inomutsa extrinsic coagulation system.
Chechipiri, mushure mekunge intima yakuvara, masero e endothelial anoora, anofa, uye anobuda, zvichiratidza collagen fibers pasi pe endothelium, nokudaro zvichitanga coagulation factor XII ye endogenous coagulation system uye kutanga endogenous coagulation system. Pamusoro pezvo, intima yakakuvara inova yakaoma, izvo zvinoita kuti platelet irambe ichiiswa uye inamatire. Mushure mekunge maplatelet akabatana abvaruka, zvinhu zvakasiyana-siyana zveplatelet zvinoburitswa, uye maitiro ese ecoagulation anovhurwa, zvichiita kuti ropa rivhare uye riite thrombus.
Zvinhu zvakasiyana-siyana zvemuviri, zvemakemikari uye zvehupenyu zvinogona kukonzera kukuvara kwemoyo, zvakaita se endocarditis munguruve erysipelas, pulmonary vasculitis mubovine pneumonia, equine parasitic arteritis, kubaiwa jekiseni kakawanda muchikamu chimwe chete chetsinga, Kukuvara uye kuboorwa kwemadziro etsinga yeropa panguva yekuvhiyiwa.

2. Kuchinja kwemamiriro ekuyerera kweropa

Zvikuru zvinoreva kuyerera kweropa zvishoma nezvishoma, kuumbwa kwemhepo inoyerera uye kumira kweropa.
Mumamiriro ezvinhu akajairwa, kufamba kweropa kunokurumidza, uye masero matsvuku eropa, maplatelet nezvimwe zvikamu zvinoungana pakati petsinga yeropa, iyo inonzi axial flow; kana kufamba kweropa kukadzikira, masero matsvuku eropa nemaplatelet anoyerera pedyo nemadziro etsinga yeropa, inonzi side flow, iyo inowedzera thrombosis.
Kuyerera kweropa kunodzikira, uye masero e endothelial ane oxygen yakanyanya, zvichikonzera kuora uye kudonha kwemasero e endothelial, kurasikirwa nebasa rawo rekugadzira nekuburitsa zvinhu zvinorwisa ropa, uye kuratidzwa kwecollagen, iyo inomutsa system yekugwamba uye inokurudzira thrombosis.
Kufamba kweropa zvishoma nezvishoma kunogonawo kuita kuti thrombus yakagadzirwa igadziriswe nyore nyore pamadziro etsinga dzeropa uye irambe ichiwedzera.

Saka, thrombus inowanzo itika mutsinga dzine ropa rinoyerera zvishoma nezvishoma uye dzinokurumidza kuyerera (pamavharuvhu etsinga). Kuyerera kweropa mutsinga kunokurumidza, uye thrombus haiwanzoonekwa. Zvichienderana nehuwandu, kuitika kwe venous thrombosis kwakapetwa ka4 kupfuura kwe arterial thrombosis, uye venous thrombosis inowanzo itika mukushaya simba kwemoyo, mushure mekuvhiyiwa kana mumhuka dzinorwara dzakarara mudendere kwenguva yakareba.
Saka, zvakakosha zvikuru kubatsira mhuka dzinorwara dzave dzakarara pasi kwenguva yakareba uye mushure mekuvhiyiwa kuti dziite mamwe mabasa akakodzera kudzivirira thrombosis.
3. Kuchinja kwezvimiro zveropa.

Zvinonyanya kureva kuwedzera kwekugwamba kweropa. Zvakadai sekutsva kwakanyanya, kupera mvura mumuviri, nezvimwewo, kuomesa ropa, kukuvara kwakanyanya, mushure mekusununguka, uye kurasikirwa neropa zvakanyanya mushure mekuvhiyiwa kukuru zvinogona kuwedzera huwandu hwemaplatelet muropa, kuwedzera viscosity yeropa, uye kuwedzera huwandu hwefibrinogen, thrombin nezvimwe zvinhu zvinogwamba muplasma Kuwedzera. Zvinhu izvi zvinogona kukurudzira thrombosis.