Thrombosis yawanci yana da waɗannan yanayi guda uku:

1. Raunin zuciya da jijiyoyin jini

Intima na zuciya da jijiyoyin jini na yau da kullun yana nan lafiya kuma yana da santsi, kuma ƙwayoyin endothelial marasa lalacewa na iya hana mannewar platelets da hana coagulation. Idan membrane na ciki ya lalace, tsarin coagulation zai iya kunnawa ta hanyoyi da yawa.

Intima na farko da ya lalace yana fitar da sinadarin coagulation na nama (coagulation factor III), wanda ke kunna tsarin coagulation na waje.
Abu na biyu, bayan lalacewar intima, ƙwayoyin endothelial suna fuskantar lalacewa, necrosis, da zubar jini, suna fallasa zaruruwan collagen a ƙarƙashin endothelium, ta haka suna kunna coagulation factor XII na tsarin coagulation na endogenous kuma suna fara tsarin coagulation na endogenous. Bugu da ƙari, intima da ya lalace yana zama mai kauri, wanda ke taimakawa wajen adana platelets da mannewa. Bayan fashewar platelets da aka manne, ana fitar da nau'ikan abubuwan platelets iri-iri, kuma dukkan tsarin coagulation yana kunnawa, wanda ke haifar da haɗuwa da samar da thrombus.
Abubuwa daban-daban na zahiri, sinadarai da na halitta na iya haifar da lalacewar jijiyoyin zuciya, kamar endocarditis a cikin erysipelas na alade, vasculitis na huhu a cikin ciwon huhu na shanu, cutar arteritis ta equine, allurar da aka maimaita a cikin wannan ɓangaren na jijiyar, Rauni da huda bangon jijiyoyin jini yayin tiyata.

2. Canje-canje a yanayin kwararar jini

Ainihin yana nufin jinkirin kwararar jini, samuwar vortex da kuma dakatar da kwararar jini.
A cikin yanayi na yau da kullun, yawan kwararar jini yana da sauri, kuma ƙwayoyin jini ja, platelets da sauran abubuwan haɗin suna taruwa a tsakiyar jijiyoyin jini, wanda ake kira kwararar axial; lokacin da yawan kwararar jini ya ragu, ƙwayoyin jini ja da platelets za su gudana kusa da bangon jijiyoyin jini, wanda ake kira kwararar gefe, wanda ke ƙara haɗarin thrombosis.
Gudun jini yana raguwa, kuma ƙwayoyin endothelial suna da matuƙar rashin isasshen ruwa, wanda ke haifar da lalacewa da kuma toshewar ƙwayoyin endothelial, asarar aikinsu na haɗa sinadarai da kuma sakin abubuwan hana ɗaukar jini, da kuma fallasa sinadarin collagen, wanda ke kunna tsarin haɗin jini da kuma haɓaka thrombosis.
Jinin da ke gudana a hankali yana iya sa thrombus ɗin da aka samar ya zama mai sauƙin gyarawa a bangon jijiyoyin jini kuma ya ci gaba da ƙaruwa.

Saboda haka, thrombus yakan faru ne a cikin jijiyoyin jini masu saurin kwararar jini da kuma saurin kwararar ruwa (a cikin bawuloli na jijiyoyin jini). Guduwar jinin aorta yana da sauri, kuma ba kasafai ake ganin thrombus ba. A cewar kididdiga, faruwar thrombus na jijiyoyin jini ya ninka na thrombus sau 4, kuma thrombus na jijiyoyin jini yakan faru ne a cikin gazawar zuciya, bayan tiyata ko a cikin dabbobin da ba su da lafiya da ke kwance a gida na dogon lokaci.
Saboda haka, yana da matuƙar muhimmanci a taimaki dabbobin da suka daɗe suna kwanciya bayan tiyata don yin wasu ayyukan da suka dace don hana thrombosis.
3. Canje-canje a cikin halayen jini.

Mafi mahimmanci yana nufin ƙaruwar zubar jini. Kamar ƙonewa mai yawa, bushewar jiki, da sauransu, tattara jini, mummunan rauni, bayan haihuwa, da kuma zubar jini mai tsanani bayan manyan tiyata na iya ƙara yawan platelets a cikin jini, ƙara danko na jini, da kuma ƙara yawan fibrinogen, thrombin da sauran abubuwan da ke haifar da zubar jini a cikin jini. Waɗannan abubuwan na iya haifar da thrombosis.