Isibindi siyindawo yokwenza izinto ezahlukahlukene zokujiya, futhi singahlanganisa futhi sivimbele ama-fibrin lysates kanye nezinto ezilwa ne-fibrinolytic, futhi sidlale indima yokulawula ekugcineni ibhalansi eguquguqukayo yesistimu yokujiya kanye neyokuvimbela ukujiya. Ukutholwa kwezinkomba zokujiya kwegazi ezigulini ezine-hepatitis B kubonise ukuthi akukho mehluko obalulekile ku-PTAPTT ezigulini ezine-hepatitis B engapheli uma kuqhathaniswa neqembu lokulawula elijwayelekile (P>0.05), kodwa kwakukhona umehluko obalulekile ku-FIB (P<0.05). Kwakukhona umehluko obalulekile ku-PT, APTT, kanye ne-FIB phakathi kweqembu le-hepatitis B elinzima kanye neqembu lokulawula elijwayelekile (P<005P<0.01), okufakazela ukuthi ubukhali be-hepatitis B buhlobene kahle nokwehla kwamazinga e-blood coagulation factor.

Ukuhlaziywa kwezizathu zemiphumela engenhla:

1. Ngaphandle kwe-factor IV (Ca*) kanye ne-cytoplasm, ezinye izici zokuqina kwe-plasma ziyakhiwa esibindini; izici zokuvimbela ukujiya kwegazi (izithibi zokuqina kwe-coagulation) njenge-ATIPC, i-2-MaI-AT, njll. nazo ziyakhiwa ukwakheka kwamaseli esibindi. Lapho amaseli esibindi onakele noma efa ngamazinga ahlukene, ikhono lesibindi lokuhlanganisa izici zokuqina kwe-coagulation kanye nezinto zokuvimbela ukujiya kwegazi liyancishiswa, futhi amazinga e-plasma alezi zinto nawo ayancishiswa, okuholela ezinkingeni endleleni yokuqina kwe-coagulation.I-PT iyisivivinyo sokuhlola uhlelo lokugoba kwangaphandle, olungabonisa izinga, umsebenzi kanye nomsebenzi we-coagulation factor IV VX ku-plasma. Ukwehla kwezici ezingenhla noma izinguquko emisebenzini yazo kanye nemisebenzi kube esinye sezizathu ze-PT ende ezigulini ezine-post-hepatitis B cirrhosis kanye ne-hepatitis B enzima. Ngakho-ke, i-PT ivame ukusetshenziswa emtholampilo ukukhombisa ukwakheka kwezici zokugoba esibindini.

2. Ngakolunye uhlangothi, ngomonakalo wamaseli esibindi kanye nokwehluleka kwesibindi ezigulini ze-hepatitis B, izinga le-plasmin ku-plasma liyakhula ngalesi sikhathi. I-Plasmin ayikwazi kuphela ukugcwalisa inani elikhulu le-fibrin, i-fibrinogen kanye nezinto eziningi zokubopha njenge-factor training, i-XXX, i-VVII,Ⅱ, njll., kodwa futhi idla inani elikhulu lezinto ezilwa nokujiya kwegazi njenge-ATⅢI-PC njalo njalo. Ngakho-ke, njengoba lesi sifo siqhubeka, i-APTT yaqhubeka isikhathi eside futhi i-FIB yehla kakhulu ezigulini ze-hepatitis B.

Ekuphetheni, ukutholakala kwezinkomba zokujiya kwegazi ezifana ne-PTAPTTFIB kubaluleke kakhulu emtholampilo ekwahluleleni isimo seziguli ezine-hepatitis B engapheli, futhi kuyinkomba yokutholakala ebucayi nethembekile.