Tsarin coagulation tsari ne na ruwa-nau'in furotin enzymatic hydrolysis tsari wanda ya ƙunshi abubuwa kusan 20, yawancin su plasma glycoproteins ne wanda hanta ke haɗa su, don haka hanta tana taka muhimmiyar rawa a cikin tsarin hemostasis a cikin jiki.Zubar da jini wata alama ce ta asibiti da aka fi sani da cutar hanta (cutar hanta), musamman ma marasa lafiya masu tsanani, kuma daya daga cikin muhimman abubuwan da ke haifar da mutuwa.
Hanta wuri ne don haɗa nau'ikan abubuwan coagulation iri-iri, kuma yana iya haɗawa da kashe fibrin lysates da abubuwan antifibrinolytic, kuma suna taka rawa wajen kiyaye ma'auni mai ƙarfi na tsarin coagulation da anticoagulation.Gano alamun haɗin jini a cikin marasa lafiya da ciwon hanta B ya nuna cewa babu wani bambanci mai mahimmanci a cikin PTAPTT a cikin marasa lafiya da ciwon hanta na kullum idan aka kwatanta da ƙungiyar kulawa ta al'ada (P> 0.05), amma akwai babban bambanci a FIB (P <0.05). ).Akwai bambance-bambance masu mahimmanci a cikin PT, APTT, da FIB tsakanin ƙungiyar hepatitis B mai tsanani da ƙungiyar kulawa ta al'ada (P<005P <0.01), wanda ya tabbatar da cewa tsananin ciwon hanta B yana da alaƙa da raguwar matakan jini na coagulation.
Binciken dalilai na sakamakon sama:
1. Sai dai factor IV (Ca *) da cytoplasm, wasu abubuwan haɗin jini na plasma suna haɗuwa a cikin hanta;Abubuwan da ke hana zubar jini (masu hana coagulation) kamar ATIPC, 2-MaI-AT, da sauransu kuma hanta ne ke haɗa su.salula kira.Lokacin da sel hanta suka lalace ko necrotic zuwa digiri daban-daban, ikon hanta don haɗa abubuwan haɗin gwiwa da abubuwan anti-coagulation yana raguwa, kuma matakan plasma na waɗannan abubuwan kuma suna raguwa, yana haifar da cikas ga tsarin coagulation.PT gwajin gwaji ne na tsarin coagulation na waje, wanda zai iya nuna matakin, aiki da aikin coagulation factor IV VX a cikin jini.Rage abubuwan da ke sama ko canje-canje a cikin ayyukansu da ayyukansu sun zama ɗaya daga cikin dalilan da ke haifar da tsawaitawar PT a cikin marasa lafiya da ke fama da ciwon hanta na B cirrhosis da kuma ciwon hanta mai tsanani. Saboda haka, PT ana amfani da shi a asibiti don yin la'akari da haɗuwa da coagulation. abubuwan da ke cikin hanta.
2. A gefe guda kuma, tare da lalacewar ƙwayoyin hanta da gazawar hanta a cikin marasa lafiya na hepatitis B, matakin plasmin a cikin jini yana karuwa a wannan lokaci.Plasmin ba zai iya yin hydrolyze mai yawa na fibrin kawai ba, fibrinogen da abubuwa masu yawa na coagulation kamar horar da abubuwa, XXX, VVII,Ⅱ, da dai sauransu, amma kuma suna cinye babban adadin abubuwan da ke hana coagulation kamar ATⅢPC da sauransu.Saboda haka, tare da zurfafa cutar, APTT ya tsawaita kuma FIB ya ragu sosai a cikin marasa lafiya na hepatitis B.
A ƙarshe, gano alamun coagulation kamar PTAPTTFIB yana da mahimmancin mahimmancin asibiti don yin la'akari da yanayin marasa lafiya da ke fama da ciwon hanta na kullum, kuma yana da mahimmanci kuma abin dogara.
Katin kasuwanci
WeChat na Sinanci
Turanci WeChat