D-dimer e nkiloe ho cross-linked fibrin clot e qhibilihisitsoeng ke plasmin. Haholo-holo e bonahatsa mosebetsi oa lytic oa fibrin. E sebelisoa haholo-holo ho hlahlobeng venous thromboembolism, deep vein thrombosis le pulmonary embolism ts'ebetsong ea bongaka. Teko ea boleng ba D-dimer e mpe, haeba teko ea bongata e lokela ho ba ka tlase ho 200μg/L.

Keketseho ea D-dimer kapa liphetho tse ntle tsa liteko hangata li bonoa mafung a amanang le hyperfibrinolysis ea bobeli, joalo ka boemo ba hypercoagulable, ho bokellana ha methapo ea mali ka har'a methapo, lefu la liphio, ho hana ho kenngoa ha litho, le kalafo ea thrombolytic. Ho phaella moo, ha ho na le thrombosis e sebetsang methapong ea mali ea 'mele, kapa mafu a tsamaeang le ts'ebetso ea fibrinolytic, D-dimer le eona e tla eketseha haholo. Mafu a tloaelehileng a kang myocardial infarction, pulmonary embolism, thrombosis ea methapo e tebileng ea maoto a tlaase, cerebral infarction jj.; mafu a mang, opereishene, mafu a hlahala, le necrosis ea lisele le tsona li lebisa ho eketseheng ha D-dimer; ho phaella moo, mafu a mang a autoimmune a batho, joalo ka rheumatic endocarditis, rheumatic arthritis, systemic Lupus erythematosus, jj., a ka boela a baka keketseho ea D-dimer.

Ntle le ho hlahloba mafu, ho lemoha D-dimer ka bongata ho ka boela ha bonts'a ka bongata phello ea thrombolytic ea lithethefatsi ts'ebetsong ea bongaka. Likarolo tsa mafu, jj., kaofela lia thusa.

Tabeng ea D-dimer e phahameng, 'mele o kotsing e kholo ea thrombosis. Nakong ena, lefu la mantlha le lokela ho fumanoa kapele kamoo ho ka khonehang, 'me lenaneo la thibelo ea thrombosis le lokela ho qaloa ho latela lintlha tsa DVT. Meriana e meng e ka khethoa bakeng sa kalafo ea ho thibela ho ruruha ha mali, joalo ka ente ea heparin calcium e boima bo tlase ba limolek'hule kapa rivaroxaban, e nang le phello e itseng ea thibelo ho thehoeng ha thrombosis. Ba nang le liso tsa thrombotic ba hloka ho etsa thrombolytic tumor kapele kamoo ho ka khonehang nakong ea khauta, 'me u hlahlobe D-dimer nako le nako.