D-dimer inotorwa kubva mu cross-linked fibrin clot yakanyungudutswa ne plasmin. Inonyanya kuratidza mashandiro e lytic e fibrin. Inonyanya kushandiswa pakuongorora venous thromboembolism, deep vein thrombosis uye pulmonary embolism mukiriniki. D-dimer qualitative test haina kunaka, kana quantitative test ichifanira kunge iri pasi pe 200μg/L.

Kuwedzera kweD-dimer kana kuti mhedzisiro yakanaka yebvunzo inowanzoonekwa muzvirwere zvine chekuita ne secondary hyperfibrinolysis, zvakaita se hypercoagulable state, disseminated intravascular coagulation, itsvo, organ transplant rejection, uye thrombolytic therapy. Pamusoro pezvo, kana paine activated thrombosis mutsinga dzeropa dzemuviri, kana zvirwere zvinoperekedzwa ne fibrinolytic activity, D-dimer ichawedzerawo zvakanyanya. Zvirwere zvakajairika zvakaita se myocardial infarction, pulmonary embolism, lower end deep vein thrombosis, cerebral infarction Etc.; zvimwe hutachiona, kuvhiyiwa, zvirwere zve bundu, uye tissue necrosis zvinotungamirawo kuwedzera D-dimer; pamusoro pezvo, zvimwe zvirwere zve autoimmune zvevanhu, zvakaita se rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, nezvimwewo, zvinogonawo kukonzera kuwedzera D-dimer.

Kuwedzera pakuongorora zvirwere, kuongororwa kwehuwandu hweD-dimer kunogonawo kuratidza huwandu hwemhedzisiro yemishonga mukurapa. Zvimwe zvezvirwere, nezvimwewo, zvese zvinobatsira.

Kana paine D-dimer yakakwira, muviri unenge uri panjodzi huru yekubatwa nethrombosis. Panguva ino, chirwere chikuru chinofanira kuongororwa nekukurumidza, uye chirongwa chekudzivirira thrombosis chinofanira kutanga zvichienderana neDVT score. Mimwe mishonga inogona kusarudzwa yekurapa kwekudzivirira kuungana kweropa, senge kubaiwa pasi peganda neheparin calcium ine huremu hwakaderera kana rivaroxaban, iyo ine simba rekudzivirira pakuumbwa kwethrombosis. Avo vane thrombotic loses vanofanira kuita thrombolytic bundu nekukurumidza mukati menguva yakanaka, uye ongorora D-dimer nguva nenguva.