Chiwindi ndi malo opangira zinthu zosiyanasiyana zolimbitsa thupi, ndipo chimatha kupanga ndi kuletsa ma fibrin lysates ndi zinthu zoletsa fibrinolytic, ndipo chimagwira ntchito yolamulira pakusunga bwino mphamvu ya magazi ndi njira yoletsa magazi kuundana. Kuzindikira kuchuluka kwa magazi kuundana mwa odwala omwe ali ndi matenda a chiwindi B kunawonetsa kuti panalibe kusiyana kwakukulu mu PTAPTT mwa odwala omwe ali ndi matenda a chiwindi B osatha poyerekeza ndi gulu lolamulira lachizolowezi (P>0.05), koma panali kusiyana kwakukulu mu FIB (P<0.05). Panali kusiyana kwakukulu mu PT, APTT, ndi FIB pakati pa gulu loopsa la chiwindi B ndi gulu lolamulira lachizolowezi (P<005P<0.01), zomwe zinatsimikizira kuti kuopsa kwa chiwindi B kunali kogwirizana bwino ndi kuchepa kwa kuchuluka kwa magazi kuundana.

Kusanthula zifukwa za zotsatira zomwe zili pamwambapa:

1. Kupatula factor IV (Ca*) ndi cytoplasm, zinthu zina zolimbitsa magazi m'magazi zimapangidwa m'chiwindi; zinthu zoletsa magazi kuundana (zoletsa magazi kuundana) monga ATIPC, 2-MaI-AT, ndi zina zotero zimapangidwanso ndi kapangidwe ka maselo m'chiwindi. Pamene maselo a chiwindi awonongeka kapena kufalikira m'magazi mosiyanasiyana, mphamvu ya chiwindi yopanga zinthu zolimbitsa magazi ndi zinthu zoletsa magazi kuundana imachepa, ndipo kuchuluka kwa zinthuzi m'magazi kumachepanso, zomwe zimapangitsa kuti pakhale zopinga pa kayendedwe ka magazi kulowa m'magazi.PT ndi mayeso owunikira dongosolo la coagulation lakunja, lomwe lingawonetse kuchuluka, ntchito, ndi ntchito ya coagulation factor IV VX mu plasma. Kuchepa kwa zinthu zomwe zili pamwambapa kapena kusintha kwa zochita ndi ntchito zawo kwakhala chimodzi mwa zifukwa zomwe zimapangitsa kuti PT ikhale yayitali kwa odwala omwe ali ndi matenda a chiwindi a B pambuyo pa matenda a chiwindi komanso matenda a chiwindi a B oopsa. Chifukwa chake, PT imagwiritsidwa ntchito kwambiri kuchipatala kuti iwonetse kapangidwe ka coagulation factors mu chiwindi.

2. Kumbali ina, chifukwa cha kuwonongeka kwa maselo a chiwindi ndi kulephera kwa chiwindi mwa odwala matenda a chiwindi B, kuchuluka kwa plasmin mu plasma kumawonjezeka panthawiyi. Plasmin sikuti imangotulutsa fibrin yambiri, fibrinogen ndi zinthu zambiri zotsekeka monga maphunziro a factor, XXX, VVII,Ⅱ, ndi zina zotero, komanso amadya zinthu zambiri zotsutsana ndi magazi monga ATⅢPC ndi zina zotero. Chifukwa chake, pamene matendawa akukulirakulira, APTT inakula kwambiri ndipo FIB inachepa kwambiri mwa odwala matenda a chiwindi B.

Pomaliza, kuzindikira zizindikiro za magazi oundana monga PTAPTTFIB kuli ndi kufunika kofunikira kwambiri pachipatala poweruza mkhalidwe wa odwala omwe ali ndi matenda a chiwindi a mtundu wa B osatha, ndipo ndi chizindikiro chodziwika bwino komanso chodalirika chozindikira.