A na-enweta D-dimer site na eriri fibrin nke plasmin na-agbaze. Ọ na-egosipụtakarị ọrụ lytic nke fibrin. A na-ejikarị ya eme ihe n'ịchọpụta thromboembolism venous, thrombosis miri emi nke akwara na pulmonary embolism n'ọrụ ahụike. Nnwale D-dimer qualitative adịghị mma, ọ bụrụ na nnwale quantitative kwesịrị ịdị obere karịa 200μg/L.

A na-ahụkarị mmụba nke nsonaazụ ule D-dimer ma ọ bụ nke dị mma n'ọrịa ndị metụtara hyperfibrinolysis nke abụọ, dịka ọnọdụ hypercoagulable, coagulation intravascular gbasaara, ọrịa akụrụ, ịjụ mgbanwe akụkụ ahụ, na ọgwụgwọ thrombolytic. Na mgbakwunye, mgbe enwere thrombosis na-arụ ọrụ na arịa ọbara nke ahụ, ma ọ bụ ọrịa ndị na-eso ọrụ fibrinolytic, D-dimer ga-abawanye nke ukwuu. Ọrịa ndị a na-ahụkarị dịka myocardial infarction, pulmonary embolism, obere nsọtụ miri emi nke akwara, ụbụrụ infarction wdg; ụfọdụ ọrịa, ịwa ahụ, ọrịa tumor, na anụ ahụ necrosis na-edugakwa na mmụba nke D-dimer; na mgbakwunye, ụfọdụ ọrịa autoimmune mmadụ, dị ka rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, wdg, nwekwara ike ibute mmụba nke D-dimer.

Na mgbakwunye na ịchọpụta ọrịa, nchọpụta ọnụọgụgụ nke D-dimer nwekwara ike igosipụta mmetụta thrombolytic nke ọgwụ n'ọrụ ahụike. Akụkụ nke ọrịa, wdg, niile bara uru.

Ọ bụrụ na D-dimer dị elu, ahụ mmadụ nọ n'ihe ize ndụ dị ukwuu nke thrombosis. N'oge a, a ga-achọpụta ọrịa mbụ ahụ ozugbo enwere ike, a ga-amalitekwa usoro mgbochi thrombosis dịka akara DVT si dị. Enwere ike ịhọrọ ụfọdụ ọgwụ maka ọgwụgwọ anticoagulation, dị ka ịgba ọgwụ heparin calcium dị ala ma ọ bụ rivaroxaban n'okpuru ala, nke nwere mmetụta mgbochi ụfọdụ na mmepe nke thrombosis. Ndị nwere ọnya thrombotic kwesịrị ịnwale etuto thrombolytic ozugbo enwere ike n'ime oge ọlaedo, ma lelee D-dimer mgbe niile.