D-dimer yog muab los ntawm cov fibrin clot uas yaj los ntawm plasmin. Nws feem ntau qhia txog kev ua haujlwm lytic ntawm fibrin. Nws feem ntau yog siv rau hauv kev kuaj mob ntawm venous thromboembolism, deep vein thrombosis thiab pulmonary embolism hauv kev kho mob. D-dimer qualitative test yog tsis zoo, yog tias quantitative test yuav tsum tsawg dua 200μg/L.

Feem ntau pom muaj D-dimer ntau ntxiv lossis cov txiaj ntsig ntawm kev kuaj mob zoo hauv cov kab mob uas cuam tshuam nrog kev ua haujlwm ntawm cov ntshav khov kho (secondary hyperfibrinolysis), xws li hypercoagulable state, disseminated intravascular coagulation, renal dissemination disrejection, organ transplant rejection, thiab thrombolytic therapy. Tsis tas li ntawd xwb, thaum muaj kev ua haujlwm ntawm cov ntshav khov hauv lub cev, lossis cov kab mob uas muaj kev ua haujlwm ntawm fibrinolytic, D-dimer kuj yuav nce ntxiv ntau heev. Cov kab mob feem ntau xws li myocardial infarction, pulmonary embolism, lower extremity deep vein thrombosis, cerebral infarction thiab lwm yam; qee qhov kev kis kab mob, phais, mob qog, thiab cov nqaij mos necrosis kuj ua rau D-dimer ntau ntxiv; tsis tas li ntawd xwb, qee cov kab mob autoimmune tib neeg, xws li rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, thiab lwm yam, kuj tseem yuav ua rau D-dimer ntau ntxiv.

Ntxiv rau kev kuaj mob, kev kuaj pom D-dimer ntau npaum li cas kuj tseem tuaj yeem qhia tau ntau npaum li cas cov tshuaj thrombolytic cuam tshuam rau kev kho mob. Cov yam ntxwv ntawm cov kab mob, thiab lwm yam, txhua yam pab tau.

Yog tias D-dimer siab dhau, lub cev muaj feem yuav mob thrombosis ntau. Lub sijhawm no, yuav tsum kuaj pom tus kab mob thawj zaug sai li sai tau, thiab yuav tsum pib ua qhov kev pab cuam tiv thaiv thrombosis raws li DVT qhab nia. Qee cov tshuaj tuaj yeem xaiv rau kev kho mob anticoagulation, xws li kev txhaj tshuaj subcutaneous ntawm cov tshuaj heparin calcium uas hnyav molecular qis lossis rivaroxaban, uas muaj qee yam kev tiv thaiv rau kev tsim cov thrombosis. Cov neeg uas muaj cov kab mob thrombotic yuav tsum tau ua kom cov qog thrombolytic sai li sai tau hauv lub sijhawm kub, thiab tshuaj xyuas D-dimer tas li.