Loaʻa ka D-dimer mai ke kāpili fibrin i hoʻopili ʻia e ka plasmin. Hōʻike nui ia i ka hana lytic o ka fibrin. Hoʻohana nui ʻia ia i ka ʻike ʻana i ka venous thromboembolism, deep vein thrombosis a me ka pulmonary embolism i ka hana lapaʻau. He maikaʻi ʻole ka hoʻāʻo qualitative D-dimer, inā pono e emi ka hoʻāʻo quantitative ma mua o 200μg/L.

ʻIke pinepine ʻia ka hoʻonui ʻia ʻana o ka D-dimer a i ʻole nā ​​hopena hoʻāʻo maikaʻi i nā maʻi e pili ana i ka hyperfibrinolysis lua, e like me ke kūlana hypercoagulable, disseminated intravascular coagulation, renal disease, organ transplant rejection, a me ka thrombolytic therapy. Eia kekahi, i ka wā e loaʻa ai ka thrombosis i hoʻāla ʻia i loko o nā kīʻaha koko o ke kino, a i ʻole nā ​​​​maʻi i hele pū ʻia me ka hana fibrinolytic, e hoʻonui nui ʻia ka D-dimer. ʻO nā maʻi maʻamau e like me ka myocardial infarction, pulmonary embolism, lower extremity deep vein thrombosis, cerebral infarction Etc.; ʻo kekahi mau maʻi, ke ʻoki kino, nā maʻi tumor, a me ka necrosis kiko e alakaʻi pū i ka hoʻonui ʻia ʻana o ka D-dimer; eia kekahi, ʻo kekahi mau maʻi autoimmune kanaka, e like me ka rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, etc., hiki ke hoʻonui i ka D-dimer.

Ma waho aʻe o ka ʻike ʻana i nā maʻi, hiki i ka ʻike ʻana o ka D-dimer ke hōʻike i ka hopena thrombolytic o nā lāʻau lapaʻau i ka hana lapaʻau. He mea kōkua nā ʻano o nā maʻi, a me nā mea ʻē aʻe.

I ke ʻano o ka D-dimer kiʻekiʻe, aia ke kino i kahi pilikia kiʻekiʻe o ka thrombosis. I kēia manawa, pono e ʻike koke ʻia ka maʻi mua, a pono e hoʻomaka ʻia ka papahana pale thrombosis e like me ka helu DVT. Hiki ke koho ʻia kekahi mau lāʻau no ka lāʻau anticoagulation, e like me ka injection subcutaneous o ka calcium heparin kaumaha haʻahaʻa a i ʻole rivaroxaban, nona ka hopena pale i ka hoʻokumu ʻia ʻana o ka thrombosis. Pono ka poʻe me nā ʻeha thrombotic e hoʻopau koke i ka tumo thrombolytic i loko o ka manawa gula, a nānā hou i ka D-dimer i kēlā me kēia manawa.