Ana samun D-dimer ne daga ƙwanƙolin fibrin da plasmin ya narke. Yana nuna aikin lytic na fibrin. Ana amfani da shi musamman wajen gano cututtukan jijiyoyin jini, thrombosis na jijiyoyin jini mai zurfi da kuma embolism na huhu a aikin asibiti. Gwajin ingancin D-dimer ba shi da kyau, idan gwajin adadi ya kamata ya zama ƙasa da 200μg/L.

Ana ganin ƙaruwar sakamakon gwaji na D-dimer ko tabbatacce sau da yawa a cikin cututtuka da suka shafi hyperfibrinolysis na biyu, kamar yanayin coagulation mai yawa, coagulation na jini da aka watsa, cututtukan koda, ƙin dashen gabobi, da kuma maganin thrombolytic. Bugu da ƙari, idan akwai thrombosis da aka kunna a cikin jijiyoyin jini na jiki, ko cututtuka tare da aikin fibrinolytic, D-dimer shi ma zai ƙaru sosai. Cututtukan da aka saba gani kamar infarction na zuciya, embolism na huhu, thrombosis na jijiyoyin jini na ƙasa, bugun kwakwalwa da sauransu; wasu cututtuka, tiyata, cututtukan ƙari, da necrosis na nama suma suna haifar da ƙaruwar D-dimer; ƙari ga haka, wasu cututtukan da ke shafar garkuwar jiki na ɗan adam, kamar rheumatic endocarditis, rheumatoid arthritis, systemic Lupus erythematosus, da sauransu, suma suna iya haifar da ƙaruwar D-dimer.

Baya ga gano cututtuka, gano adadi na D-dimer kuma yana iya nuna tasirin thrombolytic na magunguna a aikace na asibiti. Bangarorin cututtuka, da sauransu, duk suna da amfani.

Idan aka samu ƙaruwar D-dimer a jiki, jiki yana cikin haɗarin kamuwa da thrombosis. A wannan lokacin, ya kamata a gano cutar ta farko da wuri-wuri, kuma a fara shirin rigakafin thrombosis bisa ga ƙimar DVT. Ana iya zaɓar wasu magunguna don maganin hana zubar jini, kamar allurar sinadarin heparin calcium mai ƙarancin nauyin ƙwayoyin halitta ko rivaroxaban, waɗanda ke da wani tasiri na rigakafi kan samuwar thrombosis. Waɗanda ke da raunukan thrombosis suna buƙatar a yi musu tiyatar ciwon thrombolytic da wuri-wuri a cikin lokacin da ya dace, kuma a riƙa duba D-dimer akai-akai.