Coagulation disgnostic mainly include plasma prothrombin time (PT), activated partial prothrombin time (APTT), fibrinogen (FIB), thrombin time (TT), D-dimer (D-D), international standardization Ratio (INR).

PT: It mainly reflects the status of the extrinsic coagulation system, of which INR is often used to monitor oral anticoagulants. Prolongation is seen in congenital coagulation factor ⅡⅤⅦⅩ deficiency and fibrinogen deficiency, and acquired coagulation factor deficiency is mainly seen in vitamin K deficiency, severe liver disease, hyperfibrinolysis, DIC, oral anticoagulants, etc.; shortening is seen in blood hypercoagulable state and thrombosis disease, etc.

APTT: It mainly reflects the status of the endogenous coagulation system, and is often used to monitor the dosage of heparin. Increased in plasma factor VIII, factor IX and factor XI decreased levels: such as hemophilia A, hemophilia B and factor XI deficiency; decreased in hypercoagulable state: such as the entry of procoagulant substances into the blood and increased activity of coagulation factors, etc. .

FIB: mainly reflects the content of fibrinogen. Increased in acute myocardial infarction and decreased in DIC consumptive hypocoagulable dissolution period, primary fibrinolysis, severe hepatitis, and liver cirrhosis.

TT: It mainly reflects the time when fibrinogen is converted into fibrin. The increase was seen in the hyperfibrinolysis stage of DIC, with low (no) fibrinogenemia, abnormal hemoglobinemia, and increased fibrin (fibrinogen) degradation products (FDP) in the blood; the decrease had no clinical significance.

INR: The International Normalized Ratio (INR) is calculated from the prothrombin time (PT) and the International Sensitivity Index (ISI) of the assay reagent. The use of INR makes the PT measured by different laboratories and different reagents comparable, which facilitates the unification of drug standards.

The main significance of blood coagulation test for patients is to check whether there is any problem with the blood, so that doctors can grasp the patient's condition in time, and it is convenient for doctors to take correct medication and treatment. The best day for the patient to do the five coagulation tests is on an empty stomach, so that the results of the test will be more accurate. After the test, the patient should show the test results to the doctor to find out the problems of the blood and prevent many accidents.