Ho khetholla ho kopana ha mali ho kenyeletsa haholo-holo nako ea prothrombin ea plasma (PT), nako ea prothrombin e sa sebetseng (APTT), fibrinogen (FIB), nako ea thrombin (TT), D-dimer (DD), Tekanyo ea maemo a machaba (INR).

PT: E bonts'a haholo-holo boemo ba sistimi ea ho kopanya mali ka ntle, eo INR e atisang ho sebelisoa ho lekola li-anticoagulant tsa molomo. Ho lelefatsa nako ho bonoa khaellong ea congenital coagulation factor ⅡⅤⅦⅩ le khaello ea fibrinogen, 'me khaello ea acquired coagulation factor e bonoa haholo khaellong ea vithamine K, lefu le matla la sebete, hyperfibrinolysis, DIC, li-anticoagulant tsa molomo, jj.; ho khutsufala ho bonoa boemong ba hypercoagulable maling le lefung la thrombosis, jj.

APTT: E bonts'a haholo-holo boemo ba sistimi ea ho kopanya mali e sa tsoakoang, 'me hangata e sebelisoa ho lekola tekanyo ea heparin. Keketseho ea plasma factor VIII, factor IX le factor XI e fokotsehile maemong: joalo ka hemophilia A, haemophilia B le khaello ea factor XI; e fokotsehile boemong ba ho kopanya mali haholo: joalo ka ho kena ha lintho tse kang procoagulant maling le ts'ebetso e eketsehileng ea lintho tse kopanyang mali, jj.

FIB: haholo-holo e bonts'a litaba tsa fibrinogen. Keketseho ea lefu la pelo le matla le ho fokotseha ha DIC nakong ea ho qhibiliha ha mali ka lebaka la ho ja, fibrinolysis ea mantlha, lefu la sebete le matla, le cirrhosis ea sebete.

TT: Haholo-holo e bonahatsa nako eo fibrinogen e fetoloang fibrin ka eona. Keketseho e bonoe mohatong oa hyperfibrinolysis oa DIC, ka fibrinogenemia e tlase (e se nang) fibrinogenemia, hemoglobinemia e sa tloaelehang, le lihlahisoa tse eketsehileng tsa ho senyeha ha fibrin (fibrinogen) (FDP) maling; phokotseho e ne e se na bohlokoa ba kliniki.

INR: Tekanyo ea Machaba e Tloaelehileng (INR) e baloa ho tloha nakong ea prothrombin (PT) le International Sensitivity Index (ISI) ea reagent ea tlhahlobo. Tšebeliso ea INR e etsa hore PT e lekanngoe ke lilaboratori tse fapaneng le li-reagent tse fapaneng e bapisoe, e leng se nolofalletsang ho kopanngoa ha maemo a meriana.

Bohlokoa bo boholo ba tlhahlobo ea ho kopanya mali bakeng sa bakuli ke ho hlahloba hore na ho na le bothata bofe ka mali, e le hore lingaka li ka utloisisa boemo ba mokuli ka nako, 'me ho bonolo hore lingaka li nke meriana le kalafo e nepahetseng. Letsatsi le molemo ka ho fetisisa la hore mokuli a etse liteko tse hlano tsa ho kopanya mali ke ka mpeng e se nang letho, e le hore liphetho tsa tlhahlobo li be tse nepahetseng haholoanyane. Kamora tlhahlobo, mokuli o lokela ho bontša ngaka liphetho tsa liteko ho fumana mathata a mali le ho thibela likotsi tse ngata.