1. Plasma D-dimer assay ke teko ea ho utloisisa mosebetsi oa bobeli oa fibrinolytic.

Molao-motheo oa tlhahlobo: Anti-DD monoclonal antibody e koahetsoe ka likaroloana tsa latex.Haeba ho na le D-dimer ho plasma ea receptor, karabelo ea antigen-antibody e tla etsahala, 'me likaroloana tsa latex li tla kopana.Leha ho le joalo, tlhahlobo ena e ka ba e ntle bakeng sa ho tsoa mali leha e le afe ka ho thehoa ha leqeba la mali, kahoo e na le boitsebiso bo tlaase le kutloisiso e phahameng.

2. Ho na le mehloli e 'meli ea D-dimer in vivo

(1) Hypercoagulable state le hyperfibrinolysis ea bobeli;

(2) thrombolysis;

D-dimer haholo-holo e bonahatsa mosebetsi oa fibrinolytic.Keketseho kapa e ntle e bonoang ho hyperfibrinolysis ea bobeli, joalo ka hypercoagulable state, coagulation ea intravascular, lefu la renal, ho hana ho fetisoa ha setho, kalafo ea thrombolytic, jj.

3. Hafeela ho ntse ho e-na le mosebetsi o sebetsang oa thrombosis le fibrinolytic meleng ea mali ea 'mele, D-dimer e tla eketseha.

Mohlala: infarction ea myocardial, cerebral infarction, pulmonary embolism, venous thrombosis, opereishene, hlahala, ho ata ha methapo ea methapo, ts'oaetso le necrosis ea lisele li ka lebisa ho eketseha ha D-dimer.Haholo-holo ho bakuli ba tsofetseng le ba sepetlele, ka lebaka la baktheria le mafu a mang, ho bonolo ho etsa hore mali a kopane ka tsela e sa tloaelehang le ho lebisa ho eketseha ha D-dimer.

4. Ntho e ikhethang e bontšitsoeng ke D-dimer ha e bue ka ts'ebetso ea lefu le itseng le itseng, empa ho litšobotsi tse tloaelehileng tsa mafu a sehlopha sena se seholo sa mafu a nang le coagulation le fibrinolysis.

Ka khopolo, sebopeho sa "cross-linked fibrin" ke thrombosis.Leha ho le joalo, ho na le mafu a mangata a kliniki a ka 'nang a kenya tšebetsong tsamaiso ea coagulation nakong ea ketsahalo le nts'etsopele ea lefu lena.Ha fibrin e amanang le sefapano e hlahisoa, tsamaiso ea fibrinolytic e tla kenngoa ts'ebetsong 'me fibrin e amanang le sefapano e tla kenngoa ka hydrolyzed ho thibela "ho bokella" ha eona ho hoholo.(Thrombus ea bohlokoa ka ho fetisisa), e bakang D-dimer e phahameng haholo.Ka hona, D-dimer e phahameng ha se hakaalo hore ke thrombosis ea bohlokoa ea bongaka.Bakeng sa maloetse a mang kapa batho ka bomong, e ka 'na ea e-ba ts'ebetso ea pathological.