Kodi kukwezedwa kwa D-dimer kumatanthauza thrombosis?


Wolemba: Wolowa m'malo   

1. Plasma D-dimer assay ndi kuyesa kumvetsetsa ntchito yachiwiri ya fibrinolytic.

Mfundo yoyendera: Anti-DD monoclonal antibody imakutidwa ndi tinthu ta latex.Ngati pali D-dimer mu plasma yolandirira, antigen-antibody reaction imachitika, ndipo tinthu ta latex timaphatikizana.Komabe, mayesowa amatha kukhala abwino pakukhetsa magazi kulikonse komwe kumapangitsa kuti magazi aziundana, motero amakhala otsika kwambiri komanso amamva bwino kwambiri.

2. Pali magwero awiri a D-dimer mu vivo

(1) Hypercoagulable state ndi hyperfibrinolysis yachiwiri;

(2) thrombolysis;

D-dimer imawonetsa kwambiri ntchito ya fibrinolytic.Kuwonjezeka kapena zabwino zomwe zimawonedwa mu hyperfibrinolysis yachiwiri, monga hypercoagulable state, kufalitsa intravascular coagulation, matenda aimpso, kukanidwa kwa kuyika ziwalo, chithandizo cha thrombolytic, etc.

3. Malingana ngati pali thrombosis yogwira ntchito ndi fibrinolytic ntchito m'mitsempha yamagazi, D-dimer idzawonjezeka.

Mwachitsanzo: m`mnyewa wamtima infarction, infarction ubongo, m`mapapo mwanga embolism, venous thrombosis, opaleshoni, chotupa, kufalitsidwa intravascular coagulation, matenda ndi minofu necrosis kungayambitse D-dimer.Makamaka okalamba ndi odwala m'chipatala, chifukwa cha bacteremia ndi matenda ena, n'zosavuta chifukwa magazi coagulation ndi kuchititsa kuchuluka D-dimer.

4. Zomwe zimasonyezedwa ndi D-dimer sizikutanthauza ntchito mu matenda enaake, koma zizindikiro zodziwika bwino za gulu lalikulu la matenda omwe ali ndi coagulation ndi fibrinolysis.

Mwachidziwitso, mapangidwe a fibrin olumikizana ndi mtanda ndi thrombosis.Komabe, pali matenda ambiri azachipatala omwe amatha kuyambitsa dongosolo la coagulation pazochitika komanso kukula kwa matendawa.Fibrin yolumikizidwa ndi mtanda ikapangidwa, fibrinolytic system idzayatsidwa ndipo fibrin yolumikizidwa ndi mtanda imapangidwa ndi hydrolyzed kuti iteteze "kuchuluka" kwake.(matenda a thrombus), zomwe zimapangitsa D-dimer yokwezeka kwambiri.Chifukwa chake, D-dimer yokwezeka sikutanthauza thrombosis yofunika kwambiri.Kwa matenda ena kapena anthu, izi zitha kukhala njira ya pathological.