O le maualuga D-dimer o lona uiga o le thrombosis?


Tusitala: Sui   

1. Plasma D-dimer assay ose su'esu'ega e malamalama ai i le galuega lona lua o le fibrinolytic.

Fa'avae su'esu'ega: Anti-DD monoclonal antibody o lo'o ufiufi i luga ole latex particles.Afai e iai le D-dimer i le plasma receptor, o le a tupu le fa'afofoga o le antigen-antibody, ma o le a fa'apipi'i vaega latex.Ae ui i lea, o lenei suʻega e mafai ona lelei mo soʻo se toto e faʻapipiʻi ai le toto, o lea e maualalo ai le faʻapitoa ma maualuga le lagona.

2. E lua puna o D-dimer i vivo

(1) Hypercoagulable tulaga ma hyperfibrinolysis lona lua;

(2) thrombolysis;

O le D-dimer e masani ona atagia ai le galuega fibrinolytic.Faʻateleina pe lelei vaʻaia i le hyperfibrinolysis lona lua, e pei o le hypercoagulable state, faʻasalalauina o le intravascular coagulation, faʻamaʻi fatugaʻo, teteʻeina o totoga, togafitiga thrombolytic, ma isi.

3. Afai lava o loʻo i ai le thrombosis malosi ma le fibrinolytic gaioiga i totonu o le toto o le tino, o le a faʻateleina le D-dimer.

Mo se faʻataʻitaʻiga: myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, taotoga, tuma, faʻasalalauina o le intravascular coagulation, faʻamaʻi ma le necrosis o le tino e mafai ona oʻo atu ai i le D-dimer.Aemaise lava mo tagata matutua ma falemaʻi, ona o le bacteremia ma isi faʻamaʻi, e faigofie ona faʻaleagaina le toto toto ma taʻitaʻia ai le D-dimer.

4. O le faʻapitoa o loʻo atagia mai e le D-dimer e le o faʻatatau i le faʻatinoga i se faʻamaʻi faʻapitoa faʻapitoa, ae o uiga faʻapitoa masani o lenei vaega tele o faʻamaʻi faʻatasi ma le coagulation ma fibrinolysis.

I le talitonuga, o le fausiaina o fibrin fesoʻotaʻi fesoʻotaʻi o le thrombosis.Ae ui i lea, e tele faʻamaʻi faʻamaʻi e mafai ona faʻagaoioia le faiga o le coagulation i le taimi o le tupu ma le atinaʻeina o le maʻi.A maua mai le fibrin feso'ota'i, o le a fa'agaoioia le faiga fibrinolytic ma o le a fa'asusu le fibrin feso'ota'i e puipuia ai lona "fa'aputuina" tele.(thrombus taua tele), e mafua ai le maualuga o le D-dimer.O le mea lea, o le D-dimer maualuga e le o se thrombosis taua tele.Mo nisi faʻamaʻi poʻo tagata taʻitoʻatasi, atonu o se pathological process.