1. Plasma D-dimer assay ndeyekuedza kunzwisisa yechipiri fibrinolytic basa.

Inspection musimboti: Anti-DD monoclonal antibody yakaputirwa pa latex particles.Kana paine D-dimer mureceptor plasma, antigen-antibody reaction ichaitika, uye latex particles inoungana.Nekudaro, iyi bvunzo inogona kuve yakanaka kune chero kubuda ropa nekuumbwa kweropa, saka ine yakaderera chaiyo uye yakanyanya kunzwa.

2. Pane mabviro maviri eD-dimer in vivo

(1) Hypercoagulable state uye yechipiri hyperfibrinolysis;

(2) thrombolysis;

Iyo D-dimer inonyanya kuratidza fibrinolytic basa.Kuwedzera kana kwakanaka kunoonekwa mune yechipiri hyperfibrinolysis, senge hypercoagulable state, yakaparadzira intravascular coagulation, chirwere chetsvo, kurambwa kweorgan transplant, thrombolytic therapy, nezvimwe.

3. Chero bedzi kune kushingaira thrombosis uye fibrinolytic basa mumidziyo yeropa yemuviri, D-dimer ichawedzera.

Semuenzaniso: myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, kuvhiyiwa, bundu, kuparadzira intravascular coagulation, utachiona uye necrosis yetishu inogona kutungamirira kuwedzera D-dimer.Kunyanya kune vakwegura uye varwere vari muchipatara, nekuda kwebhakitiriya uye zvimwe zvirwere, zviri nyore kukonzera kusagadzikana kweropa coagulation uye kutungamirira kuwedzera D-dimer.

4. Iyo chaiyo inoratidzwa neD-dimer hairevi nezvekuita mune imwe chaiyo chirwere, asi kune yakajairika pathological maitiro eboka guru rezvirwere zvine coagulation uye fibrinolysis.

Nechepfungwa, kuumbwa kwe-cross-linked fibrin ndiyo thrombosis.Nekudaro, kune dzakawanda zvirwere zvekiriniki izvo zvinogona kumisa iyo coagulation system panguva yekuitika uye kukura kwechirwere.Kana fibrin yakabatana-yakabatana ichigadzirwa, iyo fibrinolytic system inozoitwa uye iyo-yakabatana-yakabatana fibrin inozoitwa hydrolyzed kudzivirira "kuunganidza" kwayo kukuru.(kiriniki yakakosha thrombus), zvichikonzera kukwidziridzwa kwakanyanya D-dimer.Naizvozvo, yakakwira D-dimer haisati iri iyo yekiriniki yakakosha thrombosis.Kune zvimwe zvirwere kana vanhu, inogona kunge iri pathological process.