1. Kuyedzwa kwePlasma D-dimer inzira yekuongorora mashandiro echipiri e fibrinolytic.

Nheyo yekuongorora: Anti-DD monoclonal antibody inoputirwa pazvidimbu zvelatex. Kana paine D-dimer muplasma yereceptor, antigen-antibody reaction inoitika, uye zvikamu zvelatex zvinoungana. Zvisinei, bvunzo iyi inogona kuratidza kuti ropa rinobuda riine kuumbwa kweropa rakagwamba, saka haina kunyatsojeka uye ine kunzwa kwakanyanya.

2. Kune manyuko maviri eD-dimer mumuviri

(1) Kugona kuonda kweropa zvakanyanya uye hyperfibrinolysis yechipiri;

(2) kucheneswa kweropa neropa;

D-dimer inonyanya kuratidza basa re fibrinolytic. Kuwedzera kana kunaka kunoonekwa mu secondary hyperfibrinolysis, senge hypercoagulable state, disseminated intravascular coagulation, chirwere cheitsvo, kurambwa kwenhengo dzemuviri, thrombolytic therapy, nezvimwewo.

3. Chero bedzi paine active thrombosis uye fibrinolytic activity mutsinga dzeropa dzemuviri, D-dimer ichawedzera.

Semuenzaniso: myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, kuvhiyiwa, bundu, kuvharika kweropa muropa, hutachiona uye necrosis yematishu zvinogona kukonzera kuwedzera kweD-dimer. Kunyanya kune vakwegura nevarwere vari muchipatara, nekuda kwebhakitiriya nezvimwe zvirwere, zviri nyore kukonzera kuvharika kweropa zvisina kujairika uye kukonzera kuwedzera kweD-dimer.

4. Hunhu hwakasiyana hunoratidzwa neD-dimer hahurevi kushanda kwechirwere chakati, asi hunhu hwakajairika hwezvirwere zveboka guru iri rezvirwere zvine kuvharika kweropa uye fibrinolysis.

Mupfungwa, kuumbwa kwe cross-linked fibrin ndiko kupararira kweropa. Zvisinei, kune zvirwere zvakawanda zvekurapa zvinogona kumutsa system yekugwinya kweropa panguva yekuitika uye kukura kwechirwere. Kana cross-linked fibrin yagadzirwa, system ye fibrinolytic ichashanda uye cross-linked fibrin ichanyungudutswa nemvura kuti idzivirire "kuunganidza" kwayo kukuru (kuunganidzwa kweropa) (kukonzera thrombus), zvichikonzera D-dimer yakakwira zvakanyanya. Saka, D-dimer yakakwira haisiriyo thrombosis yakakosha mukurapa. Kune zvimwe zvirwere kana vanhu, inogona kunge iri nzira yezvirwere.