1. Kuyesa kwa Plasma D-dimer ndi njira yodziwira momwe fibrinolytic imagwirira ntchito.

Mfundo yowunikira: Anti-DD monoclonal antibody imakutidwa ndi tinthu ta latex. Ngati pali D-dimer mu plasma ya receptor, antigen-antibody reaction imachitika, ndipo tinthu ta latex timasonkhana pamodzi. Komabe, mayesowa akhoza kukhala abwino ngati magazi aliwonse atuluka magazi chifukwa cha kupangika kwa magazi, kotero amakhala ndi kutsimikizika kochepa komanso kukhudzidwa kwambiri.

2. Pali magwero awiri a D-dimer mu vivo

(1) Mkhalidwe wothira magazi ambiri komanso hyperfibrinolysis yachiwiri;

(2) kutsekeka kwa magazi m'mitsempha;

D-dimer imasonyeza kwambiri ntchito ya fibrinolytic. Kuwonjezeka kapena kukhala ndi zotsatira zabwino kumawonekera mu hyperfibrinolysis yachiwiri, monga momwe magazi amathira magazi, kugawanika kwa magazi m'mitsempha, matenda a impso, kukana kuikidwa kwa ziwalo, chithandizo cha thrombolytic, ndi zina zotero.

3. Bola ngati pali thrombosis yogwira ntchito komanso fibrinolytic effect m'mitsempha yamagazi ya thupi, D-dimer idzawonjezeka.

Mwachitsanzo: matenda a mtima, matenda a ubongo, matenda a m'mapapo, matenda a venous thrombosis, opaleshoni, chotupa, matenda otsekeka m'mitsempha, matenda opatsirana komanso kufalikira kwa minofu kungayambitse kuchuluka kwa D-dimer. Makamaka kwa okalamba ndi odwala omwe ali m'chipatala, chifukwa cha matenda a bakiteriya ndi matenda ena, n'zosavuta kuyambitsa magazi osakhazikika bwino ndikupangitsa kuti D-dimer ichuluke.

4. Kudziwika bwino komwe kumawonetsedwa ndi D-dimer sikukutanthauza momwe matenda enaake amagwirira ntchito, koma ku zizindikiro zodziwika bwino za gulu lalikulu la matenda omwe ali ndi magazi oundana ndi fibrinolysis.

Mwachidziwitso, kupangika kwa cross-linked fibrin ndi thrombosis. Komabe, pali matenda ambiri azachipatala omwe angayambitse kutsekeka kwa magazi panthawi yomwe matendawa akuyamba komanso kukula. Pamene cross-linked fibrin ipangidwa, fibrinolytic system idzayamba kugwira ntchito ndipo cross-linked fibrin idzasungunuka kuti ipewe "kuchulukana" kwake (kuchuluka kwa magazi m'thupi), zomwe zimapangitsa kuti D-dimer ikhale yokwera kwambiri. Chifukwa chake, D-dimer yokwera sikutanthauza kuti thrombosis ndi yofunika kwambiri m'thupi. Kwa matenda ena kapena anthu ena, ikhoza kukhala njira yowopsa.