1. ʻO ka hoʻāʻo Plasma D-dimer kahi hoʻāʻo e hoʻomaopopo ai i ka hana fibrinolytic lua.

Kumumanaʻo nānā: Ua uhi ʻia ka antibody monoclonal anti-DD ma nā ʻāpana latex. Inā he D-dimer i loko o ka plasma receptor, e hana ʻia ka hopena antigen-antibody, a e hōʻuluʻulu ʻia nā ʻāpana latex. Eia nō naʻe, hiki i kēia hoʻāʻo ke maikaʻi no kekahi kahe koko me ka hoʻokumu ʻana o ke koko clot, no laila he haʻahaʻa kona kikoʻī a me ke kiʻekiʻe o ka ʻike.

2. Aia ʻelua mau kumu o D-dimer i loko o ke kino

(1) Ke kūlana hypercoagulable a me ka hyperfibrinolysis lua;

(2) ka hoʻoheheʻe ʻana o ka trombosis;

Hōʻike nui ka D-dimer i ka hana fibrinolytic. Hoʻonui ʻia a maikaʻi paha i ʻike ʻia i ka hyperfibrinolysis lua, e like me ke kūlana hypercoagulable, disseminated intravascular coagulation, renal disease, organ transplant rejection, thrombolytic therapy, etc.

3. Inā loaʻa ka thrombosis ikaika a me ka hana fibrinolytic i loko o nā kīʻaha koko o ke kino, e piʻi aʻe ka D-dimer.

No ka laʻana: ʻo ka myocardial infarction, ka cerebral infarction, ka pulmonary embolism, ka venous thrombosis, ke ʻoki kino, ka tumor, ka disseminated intravascular coagulation, ka maʻi a me ka tissue necrosis hiki ke alakaʻi i ka hoʻonui ʻia ʻana o ka D-dimer. ʻOi aku hoʻi no nā poʻe maʻi ʻelemakule a me nā poʻe maʻi i hoʻopaʻa ʻia ma ka haukapila, ma muli o ka bacteremia a me nā maʻi ʻē aʻe, he maʻalahi ke hana i ka coagulation koko kūpono ʻole a alakaʻi i ka hoʻonui ʻia ʻana o ka D-dimer.

4. ʻO ke ʻano kikoʻī i hōʻike ʻia e D-dimer ʻaʻole ia e pili ana i ka hana ma kahi maʻi kikoʻī, akā i nā ʻano pathological maʻamau o kēia hui nui o nā maʻi me ka coagulation a me ka fibrinolysis.

Ma ke kumumanaʻo, ʻo ka hoʻokumu ʻia ʻana o ka fibrin cross-linked he thrombosis. Eia nō naʻe, he nui nā maʻi lapaʻau e hoʻāla i ka ʻōnaehana coagulation i ka wā o ka hanana a me ka hoʻomohala ʻana o ka maʻi. Ke hana ʻia ka fibrin cross-linked, e hoʻāla ʻia ka ʻōnaehana fibrinolytic a e hydrolyzed ʻia ka fibrin cross-linked e pale aku i kona "hōʻiliʻili nui". (thrombus koʻikoʻi), e hopena ana i ka D-dimer kiʻekiʻe loa. No laila, ʻaʻole pono ka D-dimer kiʻekiʻe he thrombosis koʻikoʻi clinically. No kekahi mau maʻi a i ʻole nā ​​​​kānaka, he hana pathological paha ia.