Ka kitea te hiranga o te D-Dimer ki te aroturuki i ngā raruraru e pā ana ki te haere whakamua o te COVID-19, nō reira, he aha tana pānga ki ētahi atu mate?

1. Te toto totoka o te uaua

Kua whānuitia te whakamahinga o te D-Dimer i roto i ngā mate e pā ana ki te venous thromboembolism (VTE), pērā i te deep vein thrombosis (DVT) me te pulmonary embolism (PE). Ka taea e te whakamātautau D-Dimer kino te whakakore i te DVT, ā, ka taea hoki te whakamahi i te kukū D-Dimer hei matapae i te tere hokinga mai o te VTE. I kitea e te rangahau ko te ōwehenga mōrearea o te hokinga mai o te VTE i roto i te taupori he nui ake te kukū he 4.1 ngā wā i tērā o te taupori he kukū noa.

Ko te D-Dimer tētahi o ngā tohu kitea o te PE. He tino teitei tōna uara matapae kino, ā, ko tōna hiranga he ārai i te embolism pūkahukahu whakapeka, inā koa i ngā tūroro kāore i te tino whakapaetia. Nō reira, mō ngā tūroro e whakapaetia ana he embolism pūkahukahu whakapeka, me whakakotahi te ultrasonography o ngā uaua hohonu o ngā pito o raro me te whakamātautau D-Dimer.

2. Te toto totoka kua horapa

Ko te toto toto totoka horapa (DIC) he mate haumanu e tohuhia ana e te toto totoka me te korenga o te rere toto iti i runga i te maha o ngā mate. Ko te tukanga whanaketanga e uru ana ki ngā pūnaha maha pēnei i te toto totoka, te aukati toto totoka, me te fibrinolysis. I piki ake te D-Dimer i te wā tōmua o te hanganga o te DIC, ā, i piki haere tonu tōna kukū neke atu i te 10 ngā wā i te haere whakamua o te mate. Nō reira, ka taea te whakamahi i te D-Dimer hei tetahi o ngā tohu matua mō te tautuhi wawe me te aroturuki i te āhua o te DIC.

3. Te tapahi o te aorta

"I roto i te whakaaro tahi a ngā tohunga Hainamana mō te tātaritanga me te maimoatanga o te wehenga aorta," i kīia ko te D-Dimer, hei whakamātautau taiwhanga noa mō te wehenga aorta (AD), he mea tino nui mō te tātaritanga me te tātaritanga rerekētanga o te wehenga. Ina piki tere te D-Dimer o te tūroro, ka piki ake te tūponotanga kia tātaritia ko te AD. I roto i ngā haora 24 o te tīmatanga, ina tae te D-Dimer ki te uara matua o te 500 µg/L, ko tōna aro ki te tātaritanga o te AD whakapeka he 100%, ā, ko tōna motuhaketanga he 67%, nō reira ka taea te whakamahi hei taupū whakakore mō te tātaritanga o te AD whakapeka.

4. Te Mate Pūnaha o te Ngākau Atherosclerotic

Ko te mate manawa atherosclerotic he mate manawa e puta mai ana i te papaki toto arteriosclerotic, tae atu ki te infarction myocardial acute elevation ST-segment, te infarction myocardial acute non-ST-segment elevation, me te angina unstable. I muri i te pakaru o te papaki toto, ka rere te rauemi matua necrotic i roto i te papaki toto, ka puta he wāhanga rere toto rerekē, ka whakahohehia te pūnaha toto toto, ka piki ake te kukū D-Dimer. Ko ngā tūroro mate manawa coronary me te D-Dimer teitei ka tohu pea i te mōrearea nui ake o te AMI, ā, ka taea te whakamahi hei tohu hei tirotiro i te āhua o te ACS.

5. Te rongoā thrombolytic

I kitea i roto i te rangahau a Lawter ka taea e ngā rongoā thrombolytic te whakanui ake i te D-Dimer, ā, ko ngā panonitanga o tōna kukū i mua atu, i muri mai hoki i te thrombolysis ka taea te whakamahi hei tohu mō te aromatawai i te rongoā thrombolytic. I tere te piki o tōna ihirangi ki te taumata teitei i muri i te thrombolysis, ā, i heke iho i roto i te wā poto me te whakapainga nui o ngā tohu haumanu, e tohu ana i te whai huatanga o te maimoatanga.

- I tino piki ake te taumata o te D-Dimer i roto i te 1 hāora ki te 6 hāora i muri i te thrombolysis mō te infarction myocardial acute me te infarction roro
- I te wā o te DVT thrombolysis, ka puta te tihi o te D-Dimer i roto i ngā haora 24, i muri mai rānei