Hoa bonahala hore D-Dimer e na le bohlokoa ba ho beha leihlo bo amanang le mathata tsoelo-peleng ea COVID-19, joale e bapala karolo joang mafung a mang?

1. Venus thromboembolism

D-Dimer e sebelisitsoe haholo mafung a amanang le venous thromboembolism (VTE), joalo ka deep vein thrombosis (DVT) le pulmonary embolism (PE).Teko e mpe ea D-Dimer e ka thibela DVT, 'me khatello ea D-Dimer e ka boela ea sebelisoa ho bolela esale pele sekhahla sa ho khutla ha VTE.Phuputso e fumane hore karo-karolelano ea kotsi ea ho ipheta ha VTE ho baahi ba nang le mahloriso a phahameng e ne e le makhetlo a 4.1 ho feta a baahi ba nang le mahloriso a tloaelehileng.

D-Dimer hape ke e 'ngoe ea matšoao a ho lemoha PE.Boleng ba eona bo bobe ba ho bolela esale pele bo phahame haholo, 'me bohlokoa ba eona ke ho kenyelletsa acute pulmonary embolism, haholo-holo ho bakuli ba nang le lipelaelo tse fokolang.Ka hona, bakeng sa bakuli bao ho belaelloang hore ba na le embolism e matla ea pulmonary, ultrasound ea methapo e tebileng ea lipheletsong tse tlase le tlhahlobo ea D-Dimer e lokela ho kopanngoa.

2. Ho phatlalatsoa ha intravascular coagulation

Disseminated intravascular coagulation (DIC) ke lefu la kliniki le khetholloang ke ho tsoa mali le ho hlōleha ha microcirculatory motheong oa maloetse a mangata.Ts'ebetso ea nts'etsopele e kenyelletsa mekhoa e mengata e kang coagulation, anticoagulation, le fibrinolysis.D-Dimer e ile ea eketseha nakong ea pele ea sebopeho sa DIC, 'me mahloriso a eona a tsoela pele ho eketseha ho feta 10 ha lefu lena le ntse le tsoela pele.Ka hona, D-Dimer e ka sebelisoa e le e 'ngoe ea matšoao a mantlha bakeng sa tlhahlobo ea pele le ho lekola boemo ba DIC.

3. Aortic dissection

"Tumellano ea litsebi tsa Machaena mabapi le ho hlahlojoa le ho phekoloa ha aortic dissection" e bontšitse hore D-Dimer, e le tlhahlobo e tloaelehileng ea laboratori bakeng sa aortic dissection (AD), e bohlokoa haholo bakeng sa ho hlahlojoa le ho khetholla ka mokhoa o fapaneng oa dissection.Ha D-Dimer ea mokuli e phahama ka potlako, monyetla oa ho fumanoa e le AD oa eketseha.Nakong ea lihora tse 24 ho qala, ha D-Dimer e fihla boleng ba bohlokoa ba 500 µg/L, kutloisiso ea eona ea ho hlahloba AD ke 100%, 'me e ikhethang ke 67%, kahoo e ka sebelisoa e le index ea ho khetholla a hlobaetsang AD.

4. Atherosclerotic Cardiovascular Disease

Atherosclerotic cardiovascular disease ke lefu la pelo le bakoang ke arteriosclerotic plaque, ho akarelletsa le ST-segment elevation acute myocardial infarction, non-segment elevation acute myocardial infarction, le angina e sa tsitsang.Ka mor'a ho phatloha ha letlapa, lisebelisoa tsa mantlha tsa necrotic ka har'a letlapa li phalla, li baka likarolo tse sa tloaelehang tsa phallo ea mali, ts'ebetso ea tsamaiso ea coagulation, le ho eketseha ha khatello ea D-Dimer.Bakuli ba lefu la pelo ba nang le D-Dimer e phahameng ba ka bolela esale pele kotsi e kholo ea AMI 'me e ka sebelisoa e le pontšo ea ho bona boemo ba ACS.

5. Phekolo ea Thrombolytic

Phuputso ea Lawter e fumane hore lithethefatsi tse fapa-fapaneng tsa thrombolytic li ka eketsa D-Dimer, 'me liphetoho tsa eona pele le ka morao ho thrombolysis li ka sebelisoa e le sesupo sa ho ahlola phekolo ea thrombolytic.Likahare tsa eona li ile tsa eketseha ka potlako ho ea tlhōrōng ea tlhōrō ka mor'a thrombolysis, 'me ea khutlela morao ka nako e khutšoanyane ka ntlafatso e kholo ea matšoao a kliniki, e leng se bontšang hore phekolo e ne e sebetsa hantle.

- Boemo ba D-Dimer bo eketsehile haholo hora e le 1 ho isa ho lihora tse 6 kamora thrombolysis bakeng sa infarction e matla ea myocardial le cerebral infarction.
- Nakong ea DVT thrombolysis, tlhōrō ea D-Dimer hangata e etsahala lihora tse 24 kapa hamorao