Te hiranga haumanu
He rite tonu tōna tikanga ki te wā totohu, engari he tino aro. Ko te nuinga o ngā tikanga whakatau APTT e whakamahia ana i tēnei wā ka rerekē pea ina iti iho te tauwehe totohu i te 15% ki te 30% o te taumata noa.
(1) Te roa o te APTT: 10 hēkona te roa o te hua APTT i tērā o te mana whakahaere noa. Ko te APTT te whakamātautau tirotiro pono rawa atu mō te ngoikore o te take toto toto taketake, ā, e whakamahia ana hei kimi i te hemophilia ngawari. Ahakoa ka taea te kite i ngā taumata o te take Ⅷ: C i raro iho i te 25% o te hemophilia A, he ngoikore te aro ki te hemophilia iti-haumanu (take Ⅷ>25%) me ngā kaikawe hemophilia. Ka kitea hoki ngā hua roa i roto i ngā ngoikoretanga o te take Ⅸ (hemophilia B), Ⅺ me Ⅶ; ina piki ake ngā matū whakakore toto pēnei i ngā aukati take toto toto, ngā taumata heparin rānei, ka roa ake te prothrombin, fibrinogen me te take V, te ngoikore o te take X, engari he ngoikore te aro; ka kitea hoki te roa o te APTT i roto i ētahi atu tūroro he mate ate, he DIC, me te nui o te toto kua peia.
(2) Te whakapoto o te APTT: i kitea i roto i te DIC, te āhua prethrombotic me te mate thrombotic.
(3) Te aroturuki i te maimoatanga heparin: He tino tairongo te APTT ki te kukū o te heparin plasma, nō reira he tohu aroturuki taiwhanga e whakamahia whānuitia ana i tēnei wā. I tēnei wā, me mōhio ko te hua ine APTT me whai hononga rārangi ki te kukū o te heparin plasma i roto i te awhe rongoā, ki te kore kaua e whakamahia. I te nuinga o te wā, i te wā e rongoatia ana te heparin, he mea tika kia mau tonu te APTT ki te 1.5 ki te 3.0 ngā wā i te mana whakahaere noa.
Te tātari hua
I roto i te rongoā, e whakamahia ana te APTT me te PT hei whakamātautau tirotiro mō te mahi toto totoka. E ai ki ngā hua ine, e whā pea ngā āhuatanga e whai ake nei:
(1) He noa te APTT me te PT: Haunga ngā tāngata noa, ka kitea anake i roto i te ngoikore FXIII ira-tuku iho me te ngoikore tuarua. He mea noa ngā mea kua riro mai i roto i te mate ate kino, te pukupuku ate, te lymphoma kino, te leukemia, te paturopi anti-factor XIII, te anemia autoimmune me te anemia kino.
(2) APTT roa me te PT noa: Ko te nuinga o ngā mate toto ka puta mai i ngā hapa o te ara toto toto. Pērā i te hemophilia A, B, me te ngoikore o te tauwehenga Ⅺ; kei roto i te tohanga toto ngā paturopi anti-tauwehenga Ⅷ, Ⅸ, Ⅺ.
(3) APTT noa me te PT roa: ko te nuinga o ngā mate toto i puta mai i ngā hapa o te ara toto toto o waho, pērā i te ngoikore o te ira me te ngoikore o te factor VII i whiwhihia. Ko ngā mea i whiwhihia he mea noa i roto i te mate ate, te DIC, ngā paturopi anti-factor VII i roto i te tohanga toto me ngā rongoā anticoagulant ā-waha.
(4) He roa te APTT me te PT: ko te nuinga o ngā mate toto e puta mai ana i ngā hapa o te ara toto toto noa, pērā i te ngoikore o te ira me te korenga o te take X, V, II me te I. Ko ngā mea kua riro mai ka kitea i roto i ngā mate ate me te DIC, ā, ka whakaitihia pea ngā take X me te II ina whakamahia ngā rongoā ārai toto ā-waha. Hei tāpiri, ina he paturopi anti-take X, anti-take V me te anti-take II kei roto i te tohanga toto, ka roa ake hoki. Ina whakamahia te heparin ki te rongoā, ka roa ake te APTTT me te PT.