A cikin mata masu juna biyu na al'ada, tare da haɓaka shekarun haihuwa, fitowar zuciya yana ƙaruwa kuma juriya na gefe yana raguwa.An yi imani da cewa fitarwar zuciya ta fara karuwa a makonni 8 zuwa 10 na ciki kuma ya kai kololuwa a makonni 32 zuwa 34 na ciki, karuwar 30% zuwa 45% idan aka kwatanta da rashin ciki, kuma yana kiyaye wannan matakin har zuwa lokacin haihuwa.Rage juriya na jijiyoyin bugun jini yana rage karfin jijiya, kuma karfin jini na diastolic yana raguwa sosai, kuma bambancin bugun bugun jini yana ƙaruwa.Daga makonni 6 zuwa 10 na ciki, adadin jinin mata masu juna biyu yana karuwa tare da karuwar shekarun haihuwa, kuma yana karuwa da kusan 40% a ƙarshen ciki, amma karuwar ƙwayar plasma ya wuce adadin jan jini, plasma. yana ƙaruwa da kashi 40% zuwa 50%, kuma jajayen ƙwayoyin jini suna ƙaruwa da kashi 10% zuwa 15%.Saboda haka, a cikin al'ada ciki, jini yana diluted, bayyana a matsayin rage jini danko, rage hematocrit, da kuma ƙara erythrocyte sedimentation kudi.

Abubuwan haɗin jini Ⅱ, Ⅴ, VII, Ⅷ, IX, da Ⅹ duk suna ƙaruwa yayin daukar ciki, kuma suna iya kaiwa sau 1.5 zuwa 2.0 na al'ada a tsakiyar ciki da ƙarshen ciki, da ayyukan abubuwan coagulation Ⅺ da  raguwa.Fibrinopeptide A, fibrinopeptide B, thrombinogen, platelet factor Ⅳ da fibrinogen sun karu sosai, yayin da antithrombin Ⅲ da furotin C da furotin S suka ragu.A lokacin daukar ciki, lokacin prothrombin da lokacin da aka kunna partal prothrombin yana raguwa, kuma abun ciki na fibrinogen na plasma yana ƙaruwa sosai, wanda zai iya ƙaruwa zuwa 4-6 g / L a cikin uku na uku, wanda shine kusan 50% sama da na wanda ba mai ciki ba. lokaci.Bugu da kari, plasminogen ya karu, lokacin rushewar euglobulin ya tsawaita, kuma canje-canje na coagulation-anticoagulation ya sanya jiki a cikin yanayin hypercoagulable, wanda ke da amfani ga ingantaccen hemostasis bayan zubar da ciki a lokacin aiki.Bugu da ƙari, wasu abubuwan da za a iya zubar da jini a lokacin daukar ciki sun hada da karuwar yawan cholesterol, phospholipids da triacylglycerol a cikin jini, androgen da progesterone da aka ɓoye ta wurin mahaifa suna rage tasirin wasu masu hana coagulation jini, placenta, uterine decidua da embryos.Kasancewar abubuwan thromboplastin, da dai sauransu, na iya haɓaka jini don kasancewa a cikin yanayin hypercoagulable, kuma wannan canjin yana ƙaruwa tare da haɓaka shekarun haihuwa.Matsakaicin hypercoagulation shine ma'auni na kariya na ilimin lissafi, wanda ke da amfani don kula da fibrin a cikin arteries, bangon mahaifa da kuma villi na mahaifa, yana taimakawa wajen kiyaye mutuncin mahaifa da kuma samar da thrombus saboda tsiri, da sauƙaƙe saurin hemostasis a lokacin da bayan haihuwa., hanya ce mai mahimmanci don hana zubar jini bayan haihuwa.A lokaci guda na coagulation, sakandare fibrinolytic aiki kuma fara share thrombus a cikin igiyar ciki karkace arteries da venous sinuses da kuma hanzarta farfadowa da gyara na endometrium.