Izinkomba zokuhlolwa komsebenzi wokujiya zihlanganisa isikhathi se-prothrombin (PT), isikhathi se-thromboplastin esingasebenzi (APTT), isikhathi se-thrombin (TT), i-fibrinogen (FIB), isikhathi sokujiya (CT) kanye ne-International normalized ratio (INR), njll., izinto eziningana zingakhethwa ukwenza iphakheji, ebizwa ngokuthi into ye-coagulation X. Ngenxa yezindlela ezahlukene zokuthola ezisetshenziswa izibhedlela ezahlukene, ububanzi bokubhekisela nabo buhlukile.

Isikhathi se-PT-prothrombin

I-PT ibhekisela ekungezeni i-tissue factor (TF noma i-tissue thromboplastin) kanye ne-Ca2+ ku-plasma ukuze kuqalwe uhlelo lokujiya kwangaphandle futhi kubhekwe isikhathi sokujiya kwe-plasma. I-PT ingenye yezivivinyo zokuhlola ezisetshenziswa kakhulu emitholampilo ukuhlola umsebenzi wendlela yokujiya kwangaphandle. Inani elijwayelekile lokubhekisela liyimizuzwana eyi-10 kuya kweyi-14.

I-APTT - isikhathi se-thromboplastin esingasebenzi

I-APTT iwukwengeza i-XII factor activator, i-Ca2+, i-phospholipid ku-plasma ukuze kuqalwe indlela yokujiya kwe-plasma endogenous, futhi kuqashelwe isikhathi sokujiya kwe-plasma. I-APTT ingenye yezivivinyo zokuhlola ezisetshenziswa kakhulu emitholampilo ukuze kuhlolwe umsebenzi wendlela yokujiya kwe-intrinsic. Inani elijwayelekile lokubhekisela liyimizuzwana engama-32 kuya kwengama-43.

INR - Isilinganiso Esijwayelekile Samazwe Ngamazwe

I-INR ingamandla e-ISI wesilinganiso se-PT yesiguli esihlolwe ku-PT yokulawula okujwayelekile (i-ISI iyinkomba yokuzwela yamazwe ngamazwe, futhi i-reagent ilinganiswa ngumkhiqizi lapho iphuma efektri). I-plasma efanayo yahlolwa ngama-reagent ahlukene e-ISI emalabhorethri ahlukene, futhi imiphumela yenani le-PT yayihluke kakhulu, kodwa amanani e-INR alinganisiwe ayefana, okwenza imiphumela yafana. Inani elijwayelekile lokubhekisela lingu-0.9 kuya ku-1.1.

Isikhathi se-TT-thrombin

I-TT iwukungezwa kwe-thrombin ejwayelekile ku-plasma ukuthola isigaba sesithathu senqubo yokujiya, okubonisa izinga le-fibrinogen ku-plasma kanye nenani lezinto ezifana ne-heparin ku-plasma. Inani elijwayelekile lokubhekisela liyimizuzwana eyi-16 kuya kweyi-18.

I-FIB-fibrinogen

I-FIB iwukwengeza inani elithile le-thrombin ku-plasma evivinyiwe ukuguqula i-fibrinogen ku-plasma ibe yi-fibrin, bese kubalwa okuqukethwe yi-fibrinogen ngesimiso se-turbidimetric. Inani elijwayelekile lokubhekisela lingu-2 kuya ku-4 g/L.

Umkhiqizo wokuqothulwa kwe-FDP-plasma fibrin

I-FDP yigama elijwayelekile lemikhiqizo yokuwohloka ekhiqizwa ngemuva kokuba i-fibrin noma i-fibrinogen ibolile ngaphansi kwesenzo se-plasmin ekhiqizwa ngesikhathi se-hyperfibrinolysis. Inani elijwayelekile lokubhekisela lingu-1 kuya ku-5 mg/L.

Isikhathi sokujiya kwe-CT

I-CT ibhekisela esikhathini lapho igazi liphuma emithanjeni yegazi bese lijiya ngaphandle kokusebenzisa i-vitro. Inquma ngokuyinhloko ukuthi izici ezahlukahlukene zokujiya endleleni yokujiya kwangaphakathi azikho yini, ukuthi umsebenzi wazo ujwayelekile, noma ukuthi kukhona yini ukwanda kwezinto ezilwa nokujiya kwamangqamuzana.