Fihirisar Bincike Na Ayyukan Coagulation na Jini


Marubuci: Magaji   

Likitoci ne suka ba da umarnin gano coagulation na jini akai-akai.Marasa lafiya da ke da wasu yanayi na likita ko waɗanda ke shan magungunan anticoagulant suna buƙatar sa ido kan coagulation na jini.Amma menene ma'anar lambobi da yawa?Wadanne alamomi ya kamata a kula da su a asibiti don cututtuka daban-daban?

Ma'anar gwajin aikin coagulation sun haɗa da lokacin prothrombin (PT), lokacin thromboplastin da aka kunna (APTT), lokacin thrombin (TT), fibrinogen (FIB), lokacin clotting (CT) da rabo na al'ada na duniya (INR), da sauransu, abubuwa da yawa na iya zama. zaba don yin kunshin, wanda ake kira coagulation X abu.Saboda hanyoyin gano mabambantan da asibitoci daban-daban ke amfani da su, ma'anar ma'anar ma sun bambanta.

PT-prothrombin lokaci

PT yana nufin ƙara ƙwayar nama (TF ko nama thromboplastin) da Ca2 + zuwa plasma don fara tsarin haɗin gwiwa na waje da kuma lura da lokacin coagulation na plasma.PT yana daya daga cikin gwaje-gwajen da aka fi amfani da su a cikin aikin asibiti don kimanta aikin hanyar coagulation na extrinsic.Ƙimar magana ta al'ada ita ce 10 zuwa 14 seconds.

APTT - lokacin thromboplastin mai kunnawa

APTT shine ƙara XII factor activator, Ca2+, phospholipid zuwa plasma don fara hanyar haɗin jini na endogenous, da kuma lura da lokacin haɗin jini.APTT kuma shine ɗayan gwaje-gwajen gwaji da aka fi amfani da su a cikin aikin asibiti don kimanta aikin hanyar coagulation na ciki.Ƙimar magana ta al'ada ita ce 32 zuwa 43 seconds.

INR - Ratio Mai Daidaitawa na Ƙasashen Duniya

INR ita ce ikon ISI na rabon PT na majinyacin da aka gwada zuwa PT na kulawa ta al'ada (ISI shine ma'aunin ji na kasa da kasa, kuma mai yin reagent yana daidaita shi ta hanyar masana'anta lokacin da ya bar masana'anta).An gwada plasma iri ɗaya tare da reagents na ISI daban-daban a cikin dakunan gwaje-gwaje daban-daban, kuma sakamakon ƙimar PT ya bambanta sosai, amma ƙimar INR da aka auna iri ɗaya ce, wanda ya sa sakamakon ya zama daidai.Ƙimar magana ta al'ada ita ce 0.9 zuwa 1.1.

TT-thrombin lokaci

TT shine ƙari na daidaitaccen thrombin zuwa plasma don gano mataki na uku na tsarin coagulation, yana nuna matakin fibrinogen a cikin plasma da adadin abubuwan da ke cikin heparin a cikin plasma.Ƙimar magana ta al'ada ita ce 16 zuwa 18 seconds.

FIB-fibrinogen

FIB shine ƙara wani adadin thrombin zuwa plasma da aka gwada don canza fibrinogen a cikin plasma zuwa fibrin, da lissafin abubuwan da ke cikin fibrinogen ta hanyar ka'idar turbidimetric.Ƙimar magana ta al'ada ita ce 2 zuwa 4 g/L.

FDP-plasma fibrin lalata samfurin

FDP kalma ce ta gama gari don samfuran lalata da aka samar bayan fibrin ko fibrinogen ya lalace ƙarƙashin aikin plasmin da aka samar yayin hyperfibrinolysis.Matsakaicin ƙima na al'ada shine 1 zuwa 5 mg/l.

Lokacin CT-coagulation

CT yana nufin lokacin da jini ya bar tasoshin jini kuma ya yi coagulate a cikin vitro.Ya fi ƙayyade ko abubuwa daban-daban na coagulation a cikin hanyar coagulation na ciki sun rasa, ko aikin su na al'ada ne, ko kuma akwai karuwa a cikin abubuwan da ke hana jini.